Maqui Superberry Veggie Caps [Discontinued] by Novelle International

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Dry eye. It is unclear if oral maqui berry is beneficial for dry eye. Details: Preliminary clinical research in patients with moderate dry eye shows that taking maqui extract (MaquiBright) 30 mg or 60 mg by mouth daily for 60 days improves overall symptoms of dry eye by up to 72% when compared with baseline. In patients taking 60 mg daily, tear production was increased by 50% over baseline (98673). The validity of these findings is limited by the lack of a control group.
• Impaired glucose tolerance (Prediabetes). It is unclear if oral maqui berry is beneficial for improving glycemic control in adults with prediabetes. Details: One small clinical study shows that taking maqui extract (Delphinol) 180 mg once daily for 3 months does not reduce levels of fasting blood glucose, insulin, or total cholesterol when compared with baseline. Although taking this maqui extract decreased glycated hemoglobin (HbA1c) from 5.65% to 5.35%, this change is not likely to be clinically significant (98669). Furthermore, the validity of these findings is limited by the lack of a control group. More evidence is needed to rate maqui for these uses.

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POSSIBLY SAFE ...when used orally and appropriately, short-term. Maqui berry extract has been used safely in doses of up to 180 mg daily for up to 3 months (98669,98673).

PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.

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ANTIDIABETES DRUGS Interaction Rating = Minor Be watchful with this combination. Severity = Mild •  Occurrence = Possible •  Level of Evidence = B Theoretically, maqui fruit extract may increase the risk of hypoglycemia when used with antidiabetes drugs.  Details Animal research shows that maqui berry reduces fasting blood glucose. However, maqui berry extract taken orally, either as a single dose or daily for 3 months, does not decrease fasting blood glucose in prediabetic patients (98668,98669,98672). It is unknown whether it might reduce blood glucose levels in patients with diabetes.

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General ...No adverse effects have been reported; however, a thorough evaluation of safety outcomes has not been conducted.

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