SkinHealth by Dr. Garber's

There is insufficient reliable information available about the effectiveness of Eastern red cedar.

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POSSIBLY EFFECTIVE

• Benign prostatic hyperplasia (BPH). Taking rye grass pollen extract orally seems to improve symptoms such as frequency, nocturia, urgency, flow rate, dribbling, and pain in patients with mild to moderate BPH. Details: Preliminary clinical research in adults with BPH shows that taking rye grass pollen 126 mg orally two to three times daily for 12-24 weeks improves urinary flow, residual urinary volume, and prostate size when compared with baseline and placebo (5292,5294,8520). However, other preliminary clinical research disagrees (8176). Most available studies have used a specific rye grass pollen extract (Cernilton) (5292,5294,8176,8177,8520). It is not known if rye grass pollen extract is comparable to finasteride (Proscar) or alpha-blockers. However, rye grass is comparable to Pygeum and Paraprost, a Japanese prostate remedy containing L-glutamic acid, L-alanine, and aminoacetic acid (8176,8177).
• Chronic Prostatitis and chronic pelvic pain syndrome (CP/CPPS). Some research shows that taking rye grass pollen extract might relieve some symptoms of CP/CPPS. Details: Preliminary clinical research shows that taking rye grass pollen extract (Cernilton) 126 mg orally three times daily for 12 weeks improves pain, micturition, and quality of life scores, but not sexual symptoms or urine volume, when compared with placebo in patients with CP/CPPS (95162). Other low-quality clinical research also shows that taking rye grass pollen extract improves CP/CPPS symptoms when compared with baseline (5296,5293).

INSUFFICIENT RELIABLE EVIDENCE to RATE

• Constipation. It is unclear if oral rye grass is beneficial in patients with constipation. Details: One small clinical study shows that consuming whole-grain rye bread 240 grams or more daily for 3 weeks improves intestinal transit time by 23% when compared with white bread in patients with constipation. Patients consuming rye bread reported an average of 1.4 more stools per week compared with no rye bread, along with improved stool softness and ease of defecation. Consuming rye bread also improved intestinal transit time by 41% when compared with various laxatives designed to increase fecal mass or have osmotic effects (95161). More evidence is needed to rate rye grass for this use.

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POSSIBLY UNSAFE ...when used orally in large amounts (exact dose not specified). Overdose of Eastern red cedar essential oil has been associated with vomiting, convulsions, coma, and fatality (12). There is insufficient reliable information available about the safety of Eastern red cedar when used orally in smaller amounts or when applied topically.

PREGNANCY: LIKELY UNSAFE
when used orally. Eastern red cedar is contraindicated in pregnancy due to reports of abortifacient activity. The specific part or dose of Eastern red cedar associated with its abortifacient activity is unclear (12); avoid using.

LACTATION:
Insufficient reliable information available; avoid using.

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LIKELY SAFE ...when rye grass is used orally and appropriately at levels found in the diet. Rye grass is a grain used commonly in breads and cereals (95161). ...when rye grass pollen extract is used orally and appropriately. Rye grass pollen extract appears to be safe when taken as directed for up to 24 weeks (5292,5293,5294,5296,8176,8177,8520,95162). Long-term effects are unknown.

PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using rye grass pollen extract.

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General ...Orally, overdose of Eastern red cedar oil might cause burning in the stomach, vomiting, convulsions, coma, and death (12). Topically, Eastern red cedar oil might cause local allergic reactions and irritation; however, several clinical assessments of safety show that applying Eastern red cedar oil topically does not cause skin sensitization or irritation (11,98802).

Dermatologic ...Eastern red cedar oil might cause local allergic reactions and irritation when used topically; however, sevearl clinical assessments of safety show that applying Eastern red cedar oil topically does not cause skin sensitization or irritation(11,98802).

Gastrointestinal ...Orally, overdose of Eastern red cedar oil (dose not specified) might cause burning in the stomach and vomiting (12).

Neurologic/CNS ...Orally, overdose of Eastern red cedar oil (dose not specified) might cause convulsions, coma, and death (12).

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General ...Orally, rye grass and rye grass pollen are well tolerated.
Most Common Adverse Effects:
Orally: Abdominal distention, heartburn, nausea.

Gastrointestinal ...Orally, rye grass pollen extract can cause abdominal distention, heartburn, and nausea (5293).

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