| Ingredients | Amount Per Serving |
|---|---|
|
(Hoodia gordonii )
(fleshy leaf)
|
500 mg |
Below is general information about the effectiveness of the known ingredients contained in the product Hoodia Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Below is general information about the safety of the known ingredients contained in the product Hoodia Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
There is insufficient reliable information available about the safety of hoodia.
PREGNANCY AND LACTATION:
Insufficient reliable information available; avoid using.
Below is general information about the interactions of the known ingredients contained in the product Hoodia Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
Animal research shows that a steroid glycoside of hoodia, gordonoside F, increases glucose-stimulated insulin secretion by activating GPR119. This effect enhances glucose disposal (91614). Theoretically, concomitant use of hoodia with antidiabetes medications may enhance blood glucose-lowering effects and increase the risk of hypoglycemia. Some antidiabetes medications include glimepiride (Amaryl), glyburide (DiaBeta, Glynase PresTab, Micronase), insulin, pioglitazone (Actos), rosiglitazone (Avandia), chlorpropamide (Diabinese), glipizide (Glucotrol), tolbutamide (Orinase), and others.
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Clinical research shows that hoodia can increase blood pressure (18052). Theoretically, concomitant use of hoodia with antihypertensive drugs might decrease the effectiveness of the antihypertensive drugs and increase the risk of hypertension. Some antihypertensive drugs include captopril (Capoten), enalapril (Vasotec), losartan (Cozaar), valsartan (Diovan), diltiazem (Cardizem), Amlodipine (Norvasc), hydrochlorothiazide (HydroDiuril), furosemide (Lasix), and many others.
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Evidence from in vitro research shows that hoodia may stimulate beta-adrenergic receptors (91607). Also, clinical research shows that hoodia can increase blood pressure and heart rate (18052). Theoretically, using hoodia with beta-blockers might decrease the effects of these medications. Some beta-blocker drugs include atenolol (Tenormin), metoprolol (Lopressor, Toprol XL), nadolol (Corgard), and propranolol (Inderal).
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Animal research shows that a steroid glycoside of hoodia, gordonoside F, increases glucose-stimulated insulin secretion by activating GPR119 (91614). Theoretically, concomitant use of hoodia with insulin may enhance the blood glucose-lowering effects of insulin. Blood glucose levels should be monitored.
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Below is general information about the adverse effects of the known ingredients contained in the product Hoodia Extract. Some ingredients may not be listed. This information does NOT represent a recommendation for or a test of this specific product as a whole.
General ...Orally, hoodia has been reported to cause minor adverse effects including disturbances of skin sensation, headache, dizziness, giddiness, and nausea (18052). There is also concern that hoodia may increase blood pressure and heart rate (18052).
Cardiovascular ...Orally, hoodia might increase blood pressure and heart rate. Clinical research in healthy women shows that intake of purified hoodia extract containing steroid glycosides increases systolic blood pressure by 5.9 to 15.9 mmHg, diastolic blood pressure by 4.6 to 11.5 mmHg, and heart rate by 4.8 to 12.4 beats per minute (18052).
Dermatologic ...Orally, hoodia extract has been reported to cause disturbances of skin sensation (18052).
Gastrointestinal ...Orally, hoodia extract has been reported to cause nausea (18052).
Neurologic/CNS ...Orally, hoodia extract has been reported to cause headache, dizziness, and giddiness (18052).
