The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.

McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.

Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.

Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182

Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . View abstract.

Graham PH, Browne L, Cox H, Graham J. Inhalation aromatherapy during radiotherapy: results of a placebo-controlled double-blind randomized trial. J Clin Oncol 2003;21:2372-6. View abstract.

Wiebe E. A randomized trial of aromatherapy to reduce anxiety before abortion. Eff Clin Pract 2000;3(4):166-9. View abstract.

Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. View abstract.

Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. View abstract.

Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. View abstract.

Statti, G. A., Conforti, F., Sacchetti, G., Muzzoli, M., Agrimonti, C., and Menichini, F. Chemical and biological diversity of Bergamot (Citrus bergamia) in relation to environmental factors. Fitoterapia 2004;75(2):212-216. View abstract.

Bode, C. W., Zager, A., and Hansel, W. Photodynamic and photo-cross-linking potential of bergamottin. Pharmazie 2005;60(1):78-79. View abstract.

Mandalari, G., Bennett, R. N., Bisignano, G., Saija, A., Dugo, G., Lo Curto, R. B., Faulds, C. B., and Waldron, K. W. Characterization of flavonoids and pectins from bergamot (Citrus bergamia Risso) peel, a major byproduct of essential oil extraction. J.Agric.Food Chem. 1-11-2006;54(1):197-203. View abstract.

Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55. View abstract.

Hwang, J. H. [The effects of the inhalation method using essential oils on blood pressure and stress responses of clients with essential hypertension]. Taehan Kanho.Hakhoe.Chi 2006;36(7):1123-1134. View abstract.

Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. View abstract.

Valkova, S. UVB phototherapeutic modalities. Comparison of two treatments for chronic plaque psoriasis. Acta Dermatovenerol.Alp Panonica.Adriat. 2007;16(1):26-30. View abstract.

Chang, S. Y. [Effects of aroma hand massage on pain, state anxiety and depression in hospice patients with terminal cancer]. Taehan Kanho.Hakhoe.Chi 2008;38(4):493-502. View abstract.

Seo, J. Y. [The effects of aromatherapy on stress and stress responses in adolescents]. J Korean Acad.Nurs. 2009;39(3):357-365. View abstract.

Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. Fitoterapia 2011;82(3):309-316. View abstract.

Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. View abstract.

Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.Photochem.Photobiol.B 1990;7(2-4):231-250. View abstract.

Hongratanaworakit, T. Aroma-therapeutic effects of massage blended essential oils on humans. Nat.Prod.Commun. 2011;6(8):1199-1204. View abstract.

Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243. View abstract.

Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-239. View abstract.

Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97. View abstract.

Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. View abstract.

Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. View abstract.

Walsh, D. Using aromatherapy in the management of psoriasis. Nurs.Stand. 12-18-1996;11(13-15):53-56. View abstract.

Kimura, M., Mori, T., Suzuki, H., Endo, S., and Kawano, K. EEG Changes in Odor Effects after the Stress of Long Monotonous Work. Journal of International Society of Life Information Science 2001;19(2):271-274.

Gould, A. and Martin, G. N. A good odour to breathe? The effect of pleasant ambient odour on human visual vigilance. Applied Cognitive Psychology 2001;15(2):225-232.

Hansen, T. M. and Hansen, B. The effect of aromatherapy on health complaints. A randomised, controlled trial. International Journal of Essential Oil Therapeutics 2007;1(2):67-71.

Ndao DH, Ladas EJ, Cheng B, Sands SA, Snyder KT, Garvin JH Jr, Kelly KM. Inhalation aromatherapy in children and adolescents undergoing stem cell infusion: results of a placebo-controlled double-blind trial. Psychooncology. 2012 Mar;21(3):247-54. doi: 10.1002/pon.1898. Epub 2010 Dec 27. View abstract.

Bruno A, Pandolfo G, Crucitti M, et al. Low-Dose of Bergamot-Derived Polyphenolic Fraction (BPF) Did Not Improve Metabolic Parameters in Second Generation Antipsychotics-Treated Patients: Results from a 60-days Open-Label Study. Front Pharmacol 2017;8:197 View abstract.

Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. View abstract.

Gliozzi M, Walker R, Muscoli S, et al. Bergamot polyphenolic fraction enhances rosuvastatin-induced effect on LDL-cholesterol, LOX-1 expression and protein kinase B phosphorylation in patients with hyperlipidemia. Int J Cardiol 2013;170(2):140-5. View abstract.

Cai Y, Xing G, Shen T, Zhang S, Rao J, Shi R. Effects of 12-week supplementation of Citrus bergamia extracts-based formulation CitriCholess on cholesterol and body weight in older adults with dyslipidemia: a randomized, double-blind, placebo-controlled trial. Lipids Health Dis 2017;16(1):251. View abstract.

Mannucci C, Navarra M, Calapai F, Squeri R, Gangemi S, Calapai G. Clinical Pharmacology of Citrus bergamia: A Systematic Review. Phytother Res 2017;31(1):27-39. View abstract.

Navarra M, Mannucci C, Delbò M, Calapai G. Citrus bergamia essential oil: from basic research to clinical application. Front Pharmacol 2015;6:36. View abstract.

Ferlazzo N, Cirmi S, Calapai G, Ventura-Spagnolo E, Gangemi S, Navarra M. Anti-Inflammatory Activity of Citrus bergamia Derivatives: Where Do We Stand? Molecules 2016;21(10). View abstract.

Xiong M, Li Y, Tang P, Zhang Y, Cao M, Ni J, Xing M. Effectiveness of aromatherapy massage and inhalation on symptoms of depression in Chinese community-dwelling older adults. J Altern Complement Med. 2018;24(7):717-724. View abstract.

Da Pozzo E, De Leo M, Faraone I, et al. Antioxidant and antisenescence effects of bergamot juice. Oxid Med Cell Longev. 2018;2018:9395804. View abstract.

Florentin M, Liberopoulos E, Elisaf MS, Tsimihodimos V. No effect of fenugreek, bergamot and olive leaf extract on glucose homeostasis in patients with prediabetes: a randomized double-blind placebo-controlled study. Arch Med Sci Atheroscler Dis. 2019;4:e162-e166. View abstract.

McDonnell B, Newcomb P. Trial of essential oils to improve sleep for patients in cardiac rehabilitation. J Altern Complement Med. 2019;25(12):1193-1199. View abstract.

Rombolà L, Scuteri D, Adornetto A, et al. Anxiolytic-like effects of bergamot essential oil are insensitive to flumazenil in rats. Evid Based Complement Alternat Med. 2019;2019:2156873. View abstract.

Cicero AFG, Fogacci F, Bove M, Giovannini M, Borghi C. Three-arm, placebo-controlled, randomized clinical trial evaluating the metabolic effect of a combined nutraceutical containing a bergamot standardized flavonoid extract in dyslipidemic overweight subjects. Phytother Res. 2019;33(8):2094-2101. View abstract.

Hawkins JR, Weatherby N, Wrye B, Ujcich Ward KU. Bergamot aromatherapy for medical office-induced anxiety among children with an autism spectrum disorder: A randomized, controlled, blinded clinical trial. Holist Nurs Pract. 2019;33(5):285-294. View abstract.

De Leo M, Piragine E, Pirone A, et al. Protective effects of bergamot (Citrus bergamia Risso & Poiteau) juice in rats fed with high-fat diet. Planta Med. 2020;86(3):180-189. View abstract.

Toth PP, Patti AM, Nikolic D, et al. Bergamot reduces plasma lipids, atherogenic small dense LDL, and subclinical atherosclerosis in subjects with moderate hypercholesterolemia: A 6 months prospective study. Front Pharmacol. 2016;6:299. View abstract.

Musolino V, Gliozzi M, Bombardelli E, et al. The synergistic effect of Citrus bergamia and Cynara cardunculus extracts on vascular inflammation and oxidative stress in non-alcoholic fatty liver disease. J Tradit Complement Med. 2020;10(3):268-274. View abstract.

Ferro Y, Montalcini T, Mazza E, et al. Randomized clinical trial: Bergamot citrus and wild cardoon reduce liver steatosis and body weight in non-diabetic individuals aged over 50 years. Front Endocrinol (Lausanne). 2020;11:494. View abstract.

Rondanelli M, Peroni G, Riva A, et al. Bergamot phytosome improved visceral fat and plasma lipid profiles in overweight and obese class I subject with mild hypercholesterolemia: A randomized placebo controlled trial. Phytother Res. 2021;35(4):2045-2056. View abstract.

Gliozzi M, Carresi C, Musolino V, et al. The effect of bergamot-derived polyphenolic fraction on LDL small dense particles and non alcoholic fatty liver disease in patients with metabolic syndrome. Advances in Biological Chemistry. 2014;4(02):129.

Pasyar N, Rambod M, Araghi F. The effect of bergamot orange essence on anxiety, salivary cortisol, and alpha amylase in patients prior to laparoscopic cholecystectomy: A controlled trial study. Complement Ther Clin Pract. 2020;39:101153. View abstract.

Navarro-Triviño FJ, Jadczak P, Ruiz-Villaverde R. Allergic contact dermatitis caused by Lavandula angustifolia and cross-reaction with Citrus bergamia essential oils in an aromatherapist. Int J Dermatol. 2021;60(2):241-243. View abstract.

Hancke J, Srivastava S, Caceres DD, Burgos RA, Alarcon P. An exploratory double-blind, randomized, placebo-controlled study to assess the efficacy of CitruSlim on body composition and lipid parameters in obese individuals. Phytother Res 2021;35(12):7039-7049. View abstract.

Riva A, Petrangolini G, Allegrini P, et al. Artichoke and Bergamot Phytosome Alliance: A Randomized Double Blind Clinical Trial in Mild Hypercholesterolemia. Nutrients 2021;14(1):108. View abstract.

Chen ML, Chen YE, Lee HF. The Effect of Bergamot Essential Oil Aromatherapy on Improving Depressive Mood and Sleep Quality in Postpartum Women: A Randomized Controlled Trial. J Nurs Res 2022;30(2):e201. View abstract.

Mojtehedi M, Salehi-Pourmehr H, Ostadrahimi A, Asnaashari S, Esmaeilpour K, Farshbaf-Khalili A. Effect of aromatherapy with essential oil of Lavandula angustifolia Mill- Citrus bergamia and mindfulness-based intervention on sexual function, anxiety, and depression in postmenopausal women: A randomized controlled trial with factorial design. Iran J Nurs Midwifery Res. 2022:392-405. View abstract.

Sadeghi-Dehsahraei H, Esmaeili Gouvarchin Ghaleh H, Mirnejad R, Parastouei K. The effect of bergamot (KoksalGarry) supplementation on lipid profiles: A systematic review and meta-analysis of randomized controlled trials. Phytother Res. 2022;36(12):4409-24. View abstract.

Hung CL, Lin YL, Chou CM, Wang CJ. Efficacy of Aromatherapy at Relieving the Work-Related Stress of Nursing Staff from Various Hospital Departments during COVID-19. Healthcare (Basel) 2023;11(2):157. View abstract.

Wakui N, Togawa C, Ichikawa K, et al. Relieving psychological stress and improving sleep quality by bergamot essential oil use before bedtime and upon awakening: A randomized crossover trial. Complement Ther Med 2023;77:102976. View abstract.

Döner SI, Gerçek H, Sert ÖA, Aytar A, Aytar A. The effects of aromatherapy massage in menopausal women with knee osteoarthritis: A randomized controlled study. Explore (NY) 2024;20(6):103014. View abstract.

Ferro Y, Maurotti S, Mazza E, et al. Citrus bergamia and Cynara cardunculus reduce serum uric acid in individuals with non-alcoholic fatty liver disease. Medicina. 2022;58(12):1728. View abstract.