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Omega-6 Fatty Acids
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Yamada, T., Strong, J. P., Ishii, T., Ueno, T., Koyama, M., Wagayama, H., Shimizu, A., Sakai, T., Malcom, G. T., and Guzman, M. A. Atherosclerosis and omega-3 fatty acids in the populations of a fishing village and a farming village in Japan. Atherosclerosis 2000;153(2):469-481. View abstract.
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Margolin, G., Huster, G., Glueck, C. J., Speirs, J., Vandegrift, J., Illig, E., Wu, J., Streicher, P., and Tracy, T. Blood pressure lowering in elderly subjects: a double-blind crossover study of omega-3 and omega-6 fatty acids. Am J Clin Nutr 1991;53(2):562-572. View abstract.
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Ventura, H. O., Milani, R. V., Lavie, C. J., Smart, F. W., Stapleton, D. D., Toups, T. S., and Price, H. L. Cyclosporine-induced hypertension. Efficacy of omega-3 fatty acids in patients after cardiac transplantation. Circulation 1993;88(5 Pt 2):II281-II285. View abstract.
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Munoz, S. E., Piegari, M., Guzman, C. A., and Eynard, A. R. Differential effects of dietary Oenothera, Zizyphus mistol, and corn oils, and essential fatty acid deficiency on the progression of a murine mammary gland adenocarcinoma. Nutrition 1999;15(3):208-212. View abstract.
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Richardson, A. J., Cyhlarova, E., and Ross, M. A. Omega-3 and omega-6 fatty acid concentrations in red blood cell membranes relate to schizotypal traits in healthy adults. Prostaglandins Leukot.Essent.Fatty Acids 2003;69(6):461-466. View abstract.
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Melnik, B. and Plewig, G. Are disturbances of omega-6-fatty acid metabolism involved in the pathogenesis of atopic dermatitis? Acta Derm.Venereol.Suppl (Stockh) 1992;176:77-85. View abstract.
66640
Assies, J., Lok, A., Bockting, C. L., Weverling, G. J., Lieverse, R., Visser, I., Abeling, N. G., Duran, M., and Schene, A. H. Fatty acids and homocysteine levels in patients with recurrent depression: an explorative pilot study. Prostaglandins Leukot.Essent.Fatty Acids 2004;70(4):349-356. View abstract.
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Hughes-Fulford, M., Tjandrawinata, R. R., Li, C. F., and Sayyah, S. Arachidonic acid, an omega-6 fatty acid, induces cytoplasmic phospholipase A2 in prostate carcinoma cells. Carcinogenesis 2005;26(9):1520-1526. View abstract.
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Mamalakis, G., Kiriakakis, M., Tsibinos, G., Hatzis, C., Flouri, S., Mantzoros, C., and Kafatos, A. Depression and serum adiponectin and adipose omega-3 and omega-6 fatty acids in adolescents. Pharmacol.Biochem.Behav. 2006;85(2):474-479. View abstract.
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Okuyama, H., Ichikawa, Y., Sun, Y., Hamazaki, T., and Lands, W. E. Cancers common in the USA are stimulated by omega 6 fatty acids and large amounts of animal fats, but suppressed by omega 3 fatty acids and cholesterol. World Rev Nutr Diet. 2007;96:143-149. View abstract.
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Godley, P. A., Campbell, M. K., Gallagher, P., Martinson, F. E., Mohler, J. L., and Sandler, R. S. Biomarkers of essential fatty acid consumption and risk of prostatic carcinoma. Cancer Epidemiol.Biomarkers Prev. 1996;5(11):889-895. View abstract.
66737
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Willatts P, Forsyth S, Agostoni C, Casaer P, Riva, E, Boehm G. Effects of long-chain PUFA supplementation in infant formula on cognitive function in later childhood. Am J Clin Nutr. 2013;98(suppl):536S-42S. View abstract.
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Lapillonne A, Pastor N, Zhuang W, Scalabrin DMF. Infants fed formula with added long chain polyunsaturated fatty acids have reduced incidence of respiratory illnesses and diarrhea during the first year of life. BMC Pediatr. 2014;14:168. View abstract.
96913
Lee E, Kim H, Kim H, Ha EH, Chang N. Association of maternal omega-6 fatty acid intake with infant birth outcomes: Korean Mothers and Children's Environmental Health (MOCEH). Nutr J 2018;17(1):47. View abstract.
96914
Wu JHY, Marklund M, Imamura F, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Fatty Acids and Outcomes Research Consortium (FORCE). Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39?740 adults from 20 prospective cohort studies. Lancet Diabetes Endocrinol 2017;5(12):965-74. View abstract.
96916
Pawelczyk T, Trafalska E, Pawelczyk A, Kotlicka-Antczak M. Differences in omega-3 and omega-6 polyunsaturated fatty acid consumption in people at ultra-high risk of psychosis, first-episode schizophrenia, and in healthy controls. Early Interv Psychiatry 2017;11(6):498-508. View abstract.
96917
Lemoine Soto CM, Woo H, Romero K, et al. Association of omega-3 and omega-6 fatty acid intake with inflammation and respiratory outcomes in COPD. Am J Resp Crit Care Med. 2018;197:A3139.
96918
Delgado GE, März W, Lorkowski S, von Schacky C, Kleber ME. Omega-6 fatty acids: opposing associations with risk-The Ludwigshafen Risk and Cardiovascular Health Study. J Clin Lipidol 2017;11(4):1082-90.e14. View abstract.
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96920
Jasani B, Simmer K, Patole SK, Rao SC. Long chain polyunsaturated fatty acid supplementation in infants born at term. Cochrane Database Syst Rev 2017;3:CD000376. View abstract.
99973
Hooper L, Al-Khudairy L, Abdelhamid AS, et al. Omega-6 fats for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2018;11:CD011094. View abstract.
99974
Harris WS, Tintle NL, Ramachandran VS. Erythrocyte n-6 fatty acids and risk for cardiovascular outcomes and total mortality in the Framingham heart study. Nutrients. 2018;10(12). pii: E2012. View abstract.
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99976
Rutting S, Papanicolaou M, Xenaki D, et al. Dietary ?-6 polyunsaturated fatty acid arachidonic acid increases inflammation, but inhibits ECM protein expression in COPD. Respir Res. 2018;19(1):211. View abstract.
99977
Rutting S, Xenaki D, Lau E, et al. Dietary omega-6, but not omega-3, polyunsaturated or saturated fatty acids increase inflammation in primary lung mesenchymal cells. Am J Physiol Lung Cell Mol Physiol. 2018;314(6):L922-L935. View abstract.
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Ziemanski JF, Wolters LR, Jones-Jordan L, Nichols JJ, Nichols KK. Relation between dietary essential fatty acid intake and dry eye disease and meibomian gland dysfunction in postmenopausal women. Am J Ophthalmol. 2018;189:29-40. View abstract.
99979
Assmann KE, Adjibade M, Hercberg S, Galan P, Kesse-Guyot E. Unsaturated fatty acid intakes during midlife are positively associated with later cognitive function in older adults with modulating effects of antioxidant supplementation. J Nutr. 2018;148(12):1938-1945. View abstract.
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Brown TJ, Brainard J, Song F, et al. Omega-3, omega-6, and total dietary polyunsaturated fat for prevention and treatment of type 2 diabetes mellitus: systematic review and meta-analysis of randomised controlled trials. BMJ. 2019;366:l4697. View abstract.
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Dong X, Li S, Chen J, Li Y, Wu Y, Zhang D. Association of dietary ω-3 and ω-6 fatty acids intake with cognitive performance in older adults: National Health and nutrition examination Survey (NHANES) 2011-2014. Nutr J. 2020;19(1):25. View abstract.
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Gardner KG, Gebretsadik T, Hartman TJ, et al. Prenatal omega-3 and omega-6 polyunsaturated fatty acids and childhood atopic dermatitis. J Allergy Clin Immunol Pract. 2020;8(3):937-944. View abstract.
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Luo J, Ge H, Sun J, Hao K, Yao W, Zhang D. Associations of dietary ?-3, ?-6 fatty acids consumption with sleep disorders and sleep duration among adults. Nutrients 2021;13(5):1475. View abstract.
107002
Cui J, Li L, Ren L, Sun J, Zhao H, Sun Y. Dietary n-3 and n-6 fatty acid intakes and NAFLD: A cross-sectional study in the United States. Asia Pac J Clin Nutr 2021;30(1):87-98. View abstract.
107003
Grytten E, Laupsa-Borge J, Bohov P, et al. Changes in lipoprotein particle subclasses, standard lipids, and apolipoproteins after supplementation with n-3 or n-6 PUFAs in abdominal obesity: A randomized double-blind crossover study. Clin Nutr 2021;40(5):2556-2575. View abstract.
107004
Lemoine C, Brigham E, Woo H, et al. Relationship between omega-3 and omega-6 fatty acid intake and chronic obstructive pulmonary disease morbidity. Ann Am Thorac Soc. 2020;17(3):378-381. View abstract.
107005
Hanson S, Thorpe G, Winstanley L, Abdelhamid AS, Hooper L; PUFAH group. Omega-3, omega-6 and total dietary polyunsaturated fat on cancer incidence: systematic review and meta-analysis of randomised trials. Br J Cancer. 2020;122(8):1260-1270. View abstract.
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Kim Y, Kim J. N-6 polyunsaturated fatty acids and risk of cancer: Accumulating evidence from prospective studies. Nutrients. 2020;12(9):2523. View abstract.
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Farinotti M, Vacchi L, Simi S, Di Pietrantonj C, Brait L, Filippini G. Dietary interventions for multiple sclerosis. Cochrane Database Syst Rev. 2012 Dec 12;12:CD004192. 2020 May 19;5:CD004192. View abstract.