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Alpha-Linolenic Acid (ALA)
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Jovanovski E, Li D, Thanh Ho HV, et al. The effect of alpha-linolenic acid on glycemic control in individuals with type 2 diabetes: A systematic review and meta-analysis of randomized controlled clinical trials. Medicine (Baltimore) 2017;96(21):e6531. doi: 10.1097/MD.0000000000006531. View abstract.
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Pranger IG, Gruppen EG, van den Berg E, et al. Intake of n-3 fatty acids and long-term outcome in renal transplant recipients: a post hoc analysis of a prospective cohort study. Br J Nutr 2016;116(12):2066-73. doi: 10.1017/S0007114516004207. Epub 2016 Dec 20. View abstract.
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Raz R, Carasso RL, Yehuda S. The influence of short-chain essential fatty acids on children with attention-deficit/hyperactivity disorder: a double-blind placebo controlled study. J Child Adolesc Psychopharmacol 2009;19(2):167-177. doi:10.1089/cap.2008.070 View abstract.
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Dubnov-Raz G, Khoury Z, Wright I, Raz R, Berger I. The effect of alpha-linolenic acid supplementation on ADHD symptoms in children: a randomized controlled double-blind study. Front Hum Neurosci 2014;8(780): 1-5. doi:10.3389/fnhum.2014.00780. View abstract.
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Dos Santos ALT, Duarte CK, Santos M, et al. Low linolenic and linoleic acid consumption are associated with chronic kidney disease in patients with type 2 diabetes. PLoS One. 2018;13(8):e0195249. View abstract.
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Zhuang P, Shou Q, Wang W, et al. Essential fatty acids linoleic acid and α-linolenic acid sex-dependently regulate glucose homeostasis in obesity. Mol Nutr Food Res. 2018;62(17):e1800448. View abstract.
103821
Pignitter M, Lindenmeier M, Andersen G, et al. Effect of 1- and 2-month high-dose alpha-linolenic acid treatment on 13 C-labeled alpha-linolenic acid incorporation and conversion in healthy subjects. Mol Nutr Food Res. 2018;62(20):e1800271. View abstract.
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Abdelhamid AS, Brown TJ, Brainard JS, et al. Omega-3 fatty acids for the primary and secondary prevention of cardiovascular disease. Cochrane Database Syst Rev. 2020;3(2):CD003177. View abstract.
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Chen H, Deng G, Zhou Q, et al. Effects of eicosapentaenoic acid and docosahexaenoic acid versus a-linolenic acid supplementation on cardiometabolic risk factors: a meta-analysis of randomized controlled trials. Food Funct. 2020;11(3):1919-1932. View abstract.
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Yue H, Qiu B, Jia M, et al. Effects of a-linolenic acid intake on blood lipid profiles:a systematic review and meta-analysis of randomized controlled trials. Crit Rev Food Sci Nutr. 2020:1-17. View abstract.
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Chen LH, Hu Q, Li G, et al. Dietary Intake and Biomarkers of a-Linolenic Acid and Mortality: A Meta-Analysis of Prospective Cohort Studies. Front Nutr 2021;8:743852. View abstract.
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Ogawa T, Sawane K, Ookoshi K, Kawashima R. Supplementation with flaxseed oil rich in alpha-linolenic acid improves verbal fluency in healthy older adults. Nutrients 2023;15(6):1499. View abstract.