Martindale W. Martindale the Extra Pharmacopoeia. Pharmaceutical Press, 1999.

La Vecchia C, Negri E, Franceschi S, Decarli A. Case-control study on influence of methionine, nitrite, and salt on gastric carcinogenesis in northern Italy. Nutr Cancer 1997;27:65-8. View abstract.

Bellamy MF, McDowell IF, Ramsey MW, et al. Hyperhomocysteinemia after an oral methionine load acutely impairs endothelial function in healthy adults. Circulation 1998;98:1848-52. View abstract.

Hladovec J, Sommerova Z, Pisarikova A. Homocysteinemia and endothelial damage after methionine load. Thromb Res 1997;88:361-4. View abstract.

Bellone J, Farello G, Bartolotta E, et al. Methionine potentiates both basal and GHRH-induced GH secretion in children. Clin Endocrinol (Oxf) 1997;47:61-4. View abstract.

Vale JA, Meredith TJ, Goulding R. Treatment of acetaminophen poisoning. The use of oral methionine. Arch Intern Med 1981;141:394-6. View abstract.

Christensen B, Guttormsen AB, Schneede J, et al. Preoperative methionine loading enhances restoration of the cobalamin-dependent enzyme methionine synthase after nitrous oxide anesthesia. Anesthesiology 1994;80:1046-56. View abstract.

Meakins TS, Persaud C, Jackson AA. Dietary supplementation with L-methionine impairs the utilization of urea-nitrogen and increases 5-L-oxoprolinuria in normal women consuming a low protein diet. J Nutr 1998;128:720-7. View abstract.

Su LJ, Arab L. Nutritional status of folate and colon cancer risk: evidence from NHANES I epidemiologic follow-up study. Ann Epidemiol 2001;11:65-72.. View abstract.

Fuchs CS, Willett WC, Colditz GA, et al. The influence of folate and multivitamin use on the familial risk of colon cancer in women. Cancer Epidemiol Biomarkers Prev 2002;11:227-34.. View abstract.

Russman S, Junker E, Lauterburg BH. Remethylation and transsulfuration of methionine in cirrhosis: studies with L-[H3-methyl-1-C]methionine. Hepatology 2002;36:1190-6.. View abstract.

Btaiche IF, Khalidi N. Parenteral nutrition-associated liver complications in children. Pharmacotherapy 2002;22:188-211.. View abstract.

Cottington EM, LaMantia C, Stabler SP, et al. Adverse event associated with methionine loading test: a case report. Arterioscler Thromb Vasc Biol 2002;22:1046-50.. View abstract.

Anon. Should methionine be added to paracetamol formulations? Drug Ther Perspect 1997;10:11-3.

Epner DE, Morrow S, Wilcox M, Houghton JL. Nutrient intake and nutritional indexes in adults with metastatic cancer on a phase I clinical trial of dietary methionine restriction. Nutr Cancer 2002;42:158-66.. View abstract.

Epner DE. Can dietary methionine restriction increase the effectiveness of chemotherapy in treatment of advanced cancer? J Am Coll Nutr 2001;20:443S-9S.. View abstract.

Ward M, McNulty H, Pentieva K, et al. Fluctuations in dietary methionine intake do not alter plasma homocysteine concentrations in healthy men. J Nutr 2000;130:2653-7.. View abstract.

Kokko JP. Fluids and electrolytes. In: Goldman L, Bennett JC. Cecil Textbook of Medicine. 21st ed. Philadelphia, PA: W.B. Saunders Co. 2000:59.

Barshop BA. Homocystiniuria. In: Goldman L, Bennett JC. Cecil Textbook of Medicine. 21st ed. Philadelphia, PA: W.B. Saunders Co. 2000:1115-6.

Frosst P, Blom HJ, Milos R, et al. A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase. Nat Genet 1995;10:111-3.. View abstract.

Girelli D, Martinelli N, Pizzolo F, et al. The interaction between MTHFR 677 C-->T genotype and folate status is a determinant of coronary atherosclerosis risk. J Nutr 2003;133:1281-5. View abstract.

Moss, R. L., Haynes, A. L., Pastuszyn, A., and Glew, R. H. Methionine infusion reproduces liver injury of parenteral nutrition cholestasis. Pediatr.Res. 1999;45(5 Pt 1):664-668. View abstract.

Smulders, Y. M., Rakic, M., Slaats, E. H., Treskes, M., Sijbrands, E. J., Odekerken, D. A., Stehouwer, C. D., and Silberbusch, J. Fasting and post-methionine homocysteine levels in NIDDM. Determinants and correlations with retinopathy, albuminuria, and cardiovascular disease. Diabetes Care 1999;22(1):125-132. View abstract.

Sasamura, T., Matsuda, A., and Kokuba, Y. Effects of D-methionine-containing solution on tumor cell growth in vitro. Arzneimittelforschung. 1999;49(6):541-543. View abstract.

McAuley, D. F., Hanratty, C. G., McGurk, C., Nugent, A. G., and Johnston, G. D. Effect of methionine supplementation on endothelial function, plasma homocysteine, and lipid peroxidation. J.Toxicol.Clin.Toxicol. 1999;37(4):435-440. View abstract.

Hanratty, C. G., McGrath, L. T., McAuley, D. F., Young, I. S., and Johnston, G. D. The effects of oral methionine and homocysteine on endothelial function. Heart 2001;85(3):326-330. View abstract.

Ward, M., McNulty, H., McPartlin, J., Strain, J. J., Weir, D. G., and Scott, J. M. Effect of supplemental methionine on plasma homocysteine concentrations in healthy men: a preliminary study. Int.J.Vitam.Nutr.Res. 2001;71(1):82-86. View abstract.

L-methionine and naltrexone for insomnia. Posit.Health News 1998;(No 17):19. View abstract.

Shoob, H. D., Sargent, R. G., Thompson, S. J., Best, R. G., Drane, J. W., and Tocharoen, A. Dietary methionine is involved in the etiology of neural tube defect-affected pregnancies in humans. J.Nutr. 2001;131(10):2653-2658. View abstract.

Yaghmai, R., Kashani, A. H., Geraghty, M. T., Okoh, J., Pomper, M., Tangerman, A., Wagner, C., Stabler, S. P., Allen, R. H., Mudd, S. H., and Braverman, N. Progressive cerebral edema associated with high methionine levels and betaine therapy in a patient with cystathionine beta-synthase (CBS) deficiency. Am.J.Med.Genet. 2-15-2002;108(1):57-63. View abstract.

Lu, S., Hoestje, S. M., Choo, E. M., and Epner, D. E. Methionine restriction induces apoptosis of prostate cancer cells via the c-Jun N-terminal kinase-mediated signaling pathway. Cancer Lett. 5-8-2002;179(1):51-58. View abstract.

Trumbo, P., Schlicker, S., Yates, A. A., and Poos, M. Dietary reference intakes for energy, carbohydrate, fiber, fat, fatty acids, cholesterol, protein and amino acids. J Am.Diet.Assoc. 2002;102(11):1621-1630. View abstract.

Cellarier, E., Durando, X., Vasson, M. P., Farges, M. C., Demiden, A., Maurizis, J. C., Madelmont, J. C., and Chollet, P. Methionine dependency and cancer treatment. Cancer Treat.Rev. 2003;29(6):489-499. View abstract.

Larsson, S. C., Giovannucci, E., and Wolk, A. Methionine and vitamin B6 intake and risk of pancreatic cancer: a prospective study of Swedish women and men. Gastroenterology 2007;132(1):113-118. View abstract.

Douglas, A. P., Hamlyn, A. N., and James, O. Controlled trial of cysteamine in treatment of acute paracetamol (acetaminophen) poisoning. Lancet 1-17-1976;1(7951):111-115. View abstract.

Hamlyn, A. N., Lesna, M., Record, C. O., Smith, P. A., Watson, A. J., Meredith, T., Volans, G. N., and Crome, P. Methionine and cysteamine in paracetamol (acetaminophen) overdose, prospective controlled trial of early therapy. J.Int.Med.Res. 1981;9(3):226-231. View abstract.

Meininger, V., Flamier, A., Phan, T., Ferris, O., Uzan, A., and Lefur, G. [L-Methionine treatment of Parkinson's disease: preliminary results]. Rev.Neurol.(Paris) 1982;138(4):297-303. View abstract.

Tan, Y., Zavala, J., Sr., Xu, M., Zavala, J., Jr., and Hoffman, R. M. Serum methionine depletion without side effects by methioninase in metastatic breast cancer patients. Anticancer Res. 1996;16(6C):3937-3942. View abstract.

Shaw, G. M., Velie, E. M., and Schaffer, D. M. Is dietary intake of methionine associated with a reduction in risk for neural tube defect-affected pregnancies? Teratology 1997;56(5):295-299. View abstract.

Coelho CND, Klein NW. Methionine and neural tube closure in cultured rat embryos: morphological and biochemical analyses. Teratology 1990;42:437-451.

Essien FB and Wannaberg SL. Methionine but not folinic acid or vitamin B-12 alters the frequency of neural tube defects in Axd mutant mice. J Nutr 1993;123:27-34.

Guttuso T Jr, McDermott MP, Ng P, Kieburtz K. Effect of L-methionine on hot flashes in postmenopausal women: a randomized controlled trial. Menopause 2009;16(5):1004-8. View abstract.

De Luca C, Kharaeva Z, Raskovic D, Pastore P, Luci A, Korkina L. Coenzyme Q(10), vitamin E, selenium, and methionine in the treatment of chronic recurrent viral mucocutaneous infections. Nutrition 2012;28(5):509-14. View abstract.

Cassano N, Ferrari A, Fai D, et al. Oral supplementation with a nutraceutical containing Echinacea, methionine and antioxidant/immunostimulating compounds in patients with cutaneous viral warts. G Ital Dermatol Venereol 2011;146(3):191-5. View abstract.

Wu W, Kang S, Zhang D. Association of vitamin B6, vitamin B12 and methionine with risk of breast cancer: a dose-response meta-analysis. Br J Cancer 2013;109(7):1926-44. View abstract.

Talukdar R, Murthy HV, Reddy DN. Role of methionine containing antioxidant combination in the management of pain in chronic pancreatitis: a systematic review and meta-analysis. Pancreatology 2015;15(2):136-44. View abstract.

Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty Acids, Cholesterol, Protein, and Amino Acids. Washington, DC: The National Academies Press, 2005. Available at: https://doi.org/10.17226/10490

Passaro M, Mainini G, Ambrosio F, Sgambato R, Balbi G. Effect of a food supplement containing L-methionine on urinary tract infections in pregnancy: a prospective, multicenter observational study. J Altern Complement Med 2017;23(6):471-8. View abstract.

Campbell KC, Rehemtulla A, Sunkara P, Hamstra D, Buhnerkempe M, Ross B. Oral D-methionine protects against cisplatin-induced hearing loss in humans: phase 2 randomized clinical trial in India. Int J Audiol 2022;61(8):621-631. View abstract.

Campbell KCM, Cosenza N, Meech R, et al. D-methionine immediate and continued rescue after noise exposure does not prevent temporary threshold shift but alters cochlear and serum antioxidant levels. Int J Audiol 2022;61(9):769-777. View abstract.

Khairan P, Sobue T, Eshak ES, et al. Association of B Vitamins and Methionine Intake with the Risk of Gastric Cancer: The Japan Public Health Center-based Prospective Study. Cancer Prev Res (Phila) 2022;15(2):101-110. View abstract.

Van Puyvelde H, Dimou N, Katsikari A, et al. The association between dietary intakes of methionine, choline and betaine and breast cancer risk: A systematic review and meta-analysis. Cancer Epidemiol 2023;83:102322. View abstract.