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Syed TA, Ahmad SA, Holt AH, et al. Management of psoriasis with Aloe vera extract in a hydrophilic cream: a placebo-controlled, double-blind study. Trop Med Int Health 1996;1:505–9.. View abstract.

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Bunyapraphatsara N, Yongchaiyudha S, Rungpitarangsi V, Chokechaijaroenporn O. Antidiabetic activity of Aloe vera L juice. II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomedicine 1996;3:245-8. View abstract.

Choonhakarn C, Busaracome P, Sripanidkulchai B, et al. A prospective, randomized clinical trial comparing topical aloe vera with 0.1% triamcinolone acetonide in mild to moderate plaque psoriasis. J.Eur.Acad.Dermatol.Venereol. 2010;24:168-72. View abstract.

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Syed TA, Afzal M, and Ashfaq AS. Management of genital herpes in men with 0.5% Aloe vera extract in a hydrophilic cream. A placebo-controlled double-blind study. J Derm Treatment 1997;8(2):99-102.

Syed TA, Cheema KM, and Ahmad SA et al. Aloe vera extract 0.5% in hydrophilic cream versus aloe vera gel for the measurement of genital herpes in males. A placebo-controlled, double-blind, comparative study. Journal of the European Academy of Dermatology & Venerology 1996;7:294-95.

Odes HS, Madar Z. A double-blind trial of a celandin, aloevera and psyllium laxative preparation in adult patients with constipation. Digestion. 1991;49:65-71. View abstract.

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Huseini HF, Kianbakht S, Hajiaghaee R, et al. Anti-hyperglycemic and anti-hypercholesterolemic effects of Aloe vera leaf gel in hyperlipidemic type 2 diabetic patients: a randomized double-blind placebo-controlled clinical trial. Planta Med. 2012;78:311-6. View abstract.

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Worthington HV, Clarkson JE, Bryan G, et al. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane Database Syst Rev. 2011;(4):CD000978. View abstract.

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Hegazy SK, El-Bedewy M, Yagi A. Antifibrotic effect of aloe vera in viral infection-induced hepatic periportal fibrosis. World J Gastroenterol. 2012;18:2026-34. View abstract.

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Lee, K. H., Kim, J. H., Lim, D. S., and Kim, C. H. Anti-leukaemic and anti-mutagenic effects of di(2-ethylhexyl)phthalate isolated from Aloe vera Linne. J Pharm Pharmacol 2000;52(5):593-598. View abstract.

Singh, R. P., Dhanalakshmi, S., and Rao, A. R. Chemomodulatory action of Aloe vera on the profiles of enzymes associated with carcinogen metabolism and antioxidant status regulation in mice. Phytomedicine 2000;7(3):209-219. View abstract.

Rieger, L. and Carson, R. E. The clinical effects of saline and aloe vera rinses on periodontal surgical sites. J Okla.Dent.Assoc 2002;92(3):40-43. View abstract.

Yagi, A., Kabash, A., Okamura, N., Haraguchi, H., Moustafa, S. M., and Khalifa, T. I. Antioxidant, free radical scavenging and anti-inflammatory effects of aloesin derivatives in Aloe vera. Planta Med 2002;68(11):957-960. View abstract.

Yagi, A., Kabash, A., Mizuno, K., Moustafa, S. M., Khalifa, T. I., and Tsuji, H. Radical Scavenging Glycoprotein Inhibiting Cyclooxygenase-2 and Thromboxane A2 Synthase from Aloe vera Gel. Planta Med. 2003;69(3):269-271. View abstract.

Pecere, T., Sarinella, F., Salata, C., Gatto, B., Bet, A., Dalla, Vecchia F., Diaspro, A., Carli, M., Palumbo, M., and Palu, G. Involvement of p53 in specific anti-neuroectodermal tumor activity of aloe-emodin. Int J Cancer 10-10-2003;106(6):836-847. View abstract.

No author. Aloe vera helps ulcerative colitis. Health News 2004;10(6):2. View abstract.

Wang, Z. W., Huang, Z. S., Yang, A. P., Li, C. Y., Huang, H., Lin, X., Liu, Z. C., and Zhu, X. F. [Radioprotective effect of aloe polysaccharides on three non-tumor cell lines]. Ai.Zheng. 2005;24(4):438-442. View abstract.

Richardson, J., Smith, J. E., McIntyre, M., Thomas, R., and Pilkington, K. Aloe vera for preventing radiation-induced skin reactions: a systematic literature review. Clin Oncol.(R.Coll.Radiol.) 2005;17(6):478-484. View abstract.

Wu, J. H., Xu, C., Shan, C. Y., and Tan, R. X. Antioxidant properties and PC12 cell protective effects of APS-1, a polysaccharide from Aloe vera var. chinensis. Life Sci 1-2-2006;78(6):622-630. View abstract.

Wang, Z., Huang, Z., Wu, Q., Zhou, J., Zhu, X., Li, Q., and Liu, Z. [The modulating of aloe polysaccharides on the cell cycle and cycle regulating protein expression in X-ray irradiated non-malignant cells]. Zhong.Yao Cai. 2005;28(6):482-485. View abstract.

Lee, H. Z., Lin, C. J., Yang, W. H., Leung, W. C., and Chang, S. P. Aloe-emodin induced DNA damage through generation of reactive oxygen species in human lung carcinoma cells. Cancer Lett 7-28-2006;239(1):55-63. View abstract.

Lin, S. Y., Yang, J. H., Hsia, T. C., Lee, J. H., Chiu, T. H., Wei, Y. H., and Chung, J. G. Effect of inhibition of aloe-emodin on N-acetyltransferase activity and gene expression in human malignant melanoma cells (A375.S2). Melanoma Res 2005;15(6):489-494. View abstract.

Esua, M. F. and Rauwald, J. W. Novel bioactive maloyl glucans from aloe vera gel: isolation, structure elucidation and in vitro bioassays. Carbohydr Res 2-27-2006;341(3):355-364. View abstract.

Lin, J. G., Chen, G. W., Li, T. M., Chouh, S. T., Tan, T. W., and Chung, J. G. Aloe-emodin induces apoptosis in T24 human bladder cancer cells through the p53 dependent apoptotic pathway. J Urol 2006;175(1):343-347. View abstract.

Cardenas, C., Quesada, A. R., and Medina, M. A. Evaluation of the anti-angiogenic effect of aloe-emodin. Cell Mol.Life Sci 2006;63(24):3083-3089. View abstract.

Puentes Sanchez J., Pardo Gonzalez, C. M., Pardo Gonzalez, M. B., Navarro Casado, F. J., Puentes, Sanchez R., Mendez Gonzalez, J. M., Gonzalez, Rojo J., Juarez, Morales A., and Lopez, Fernandez, I. [Prevention of vascular ulcers and diabetic foot. Non-randomized open clinical evaluation on the effectiveness of "Mepentol Leche"]. Rev Enferm. 2006;29(10):25-30. View abstract.

Rosca-Casian, O., Parvu, M., Vlase, L., and Tamas, M. Antifungal activity of Aloe vera leaves. Fitoterapia 2007;78(3):219-222. View abstract.

Ferreira, M., Teixeira, M., Silva, E., and Selores, M. Allergic contact dermatitis to Aloe vera. Contact Dermatitis 2007;57(4):278-279. View abstract.

Worthington, H. V., Clarkson, J. E., and Eden, O. B. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane.Database.Syst.Rev. 2007;(4):CD000978. View abstract.

Choonhakarn, C., Busaracome, P., Sripanidkulchai, B., and Sarakarn, P. The efficacy of aloe vera gel in the treatment of oral lichen planus: a randomized controlled trial. Br J Dermatol 2008;158(3):573-577. View abstract.

Dannemann, K., Hecker, W., Haberland, H., Herbst, A., Galler, A., Schafer, T., Brahler, E., Kiess, W., and Kapellen, T. M. Use of complementary and alternative medicine in children with type 1 diabetes mellitus - prevalence, patterns of use, and costs. Pediatr.Diabetes 2008;9(3 Pt 1):228-235. View abstract.

Cefalu, W. T., Ye, J., and Wang, Z. Q. Efficacy of dietary supplementation with botanicals on carbohydrate metabolism in humans. Endocr.Metab Immune.Disord Drug Targets. 2008;8(2):78-81. View abstract.

Feily, A. and Namazi, M. R. Aloe vera in dermatology: a brief review. G.Ital.Dermatol.Venereol. 2009;144(1):85-91. View abstract.

Baretta, Z., Ghiotto, C., Marino, D., and Jirillo, A. Aloe-induced hypokalemia in a patient with breast cancer during chemotherapy. Ann.Oncol. 2009;20(8):1445-1446. View abstract.

Hunter, D. and Frumkin, A. Adverse reactions to vitamin E and aloe vera preparations after dermabrasion and chemical peel. Cutis 1991;47(3):193-196. View abstract.

Kumari, S., Harjai, K., and Chhibber, S. Topical treatment of Klebsiella pneumoniae B5055 induced burn wound infection in mice using natural products. J Infect.Dev Ctries. 2010;4(6):367-377. View abstract.

Salazar-Sanchez, N., Lopez-Jornet, P., Camacho-Alonso, F., and Sanchez-Siles, M. Efficacy of topical Aloe vera in patients with oral lichen planus: a randomized double-blind study. J.Oral Pathol.Med. 2010;39(10):735-740. View abstract.

Shah, S. A., DiTullio, P., Azadi, M., Shapiro, R. J., Eid, T. J., and Snyder, J. A. Effects of oral Aloe vera on electrocardiographic and blood pressure measurements. Am.J.Health Syst.Pharm. 11-15-2010;67(22):1942-1946. View abstract.

Alvarez-Perea, A., Garcia, A. P., Hernandez, A. L., de, Barrio M., and Baeza, M. L. Urticaria due to aloe vera: a new sensitizer? Ann.Allergy Asthma Immunol. 2010;105(5):404-405. View abstract.

Worthington, H. V., Clarkson, J. E., Bryan, G., Furness, S., Glenny, A. M., Littlewood, A., McCabe, M. G., Meyer, S., and Khalid, T. Interventions for preventing oral mucositis for patients with cancer receiving treatment. Cochrane.Database.Syst.Rev. 2010;(12):CD000978. View abstract.

Lee, T. and Dugoua, J. J. Nutritional supplements and their effect on glucose control. Curr.Diab.Rep. 2011;11(2):142-148. View abstract.

Gao, M., Singh, A., Macri, K., Reynolds, C., Singhal, V., Biswal, S., and Spannhake, E. W. Antioxidant components of naturally-occurring oils exhibit marked anti-inflammatory activity in epithelial cells of the human upper respiratory system. Respir.Res 2011;12:92. View abstract.

Bruce, S. and Watson, J. Evaluation of a prescription strength 4% hydroquinone/10% L-ascorbic acid treatment system for normal to oily skin. J.Drugs Dermatol. 2011;10(12):1455-1461. View abstract.

Morales-Bozo, I., Rojas, G., Ortega-Pinto, A., Espinoza, I., Soto, L., Plaza, A., Lozano, C., and Urzua, B. Evaluation of the efficacy of two mouthrinses formulated for the relief of xerostomia of diverse origin in adult subjects. Gerodontology. 2012;29(2):e1103-e1112. View abstract.

Dat, A. D., Poon, F., Pham, K. B., and Doust, J. Aloe vera for treating acute and chronic wounds. Cochrane.Database.Syst.Rev. 2012;2:CD008762. View abstract.

de Witte, P. and Lemli, L. The metabolism of anthranoid laxatives. Hepatogastroenterology 1990;37(6):601-605. View abstract.

Simao, D. A., Lima, E. D., Souza, R. S., Faria, T. V., and Azevedo, G. F. [Hand-foot syndrome induced by chemotherapy: a case study]. Rev.Bras.Enferm. 2012;65(2):374-378. View abstract.

Yongchaiyudha, S., Rungpitarangsi, V., Bunyapraphatsara, N., and Chokechaijaroenporn, O. Antidiabetic activity of Aloe vera L. juice. I. Clinical trial in new cases of diabetes mellitus. Phytomedicine. 1996;3(3):241-243. View abstract.

Bunyapraphatsara, N., Yongchaiyudha, S., Rungpitarangsi, V., and Chokechaijaroenporn, O. Antidiabetic activity of Aloe vera L. juice II. Clinical trial in diabetes mellitus patients in combination with glibenclamide. Phytomedicine. 1996;3(3):245-248. View abstract.

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Puataweepong P, Dhanachai M Dangprasert S Sithatani C Sawangsilp T Narkwong L et al. The efficacy of oral Aloe vera for radiation induced mucositis in head and neck cancer patients: a double-blind placebo controlled study. Asian Biomedicine 2009;3(4):375-382.

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Phillips T, Ongenae K Kanj L Slater-Freedberg J. A randomised study of an Aloe vera derivative gel dressing versus conventional treatment after shave biopsy excisions. Wounds 1995;7(5):200-202.

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Plemons J, Rees TD Binnie WH Wright JM. Evaluation of acemannan in providing pain relief in patients with recurrent aphthous stomatitis. Wounds 1994;6(2):4.

Akhtar M, Hatwar S. Efficacy of Aloe vera extract cream in management of burn wound. Journal of Clinical Epidemiology 1996;49(Suppl 1):24.

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Di Franco R, Sammarco E, Calvanese MG, De Natale F, Falivene S, Di Lecce A, Giugliano FM, Murino P, Manzo R, Cappabianca S, Muto P, Ravo V. Preventing the acute skin side effects in patients treated with radiotherapy for breast cancer: the use of corneometry in order to evaluate the protective effect of moisturizing creams. Radiat Oncol 2013;8:57. View abstract.

Choi HC, Kim SJ, Son KY, Oh BJ, Cho BL. Metabolic effects of aloe vera gel complex in obese prediabetes and early non-treated diabetic patients: randomized controlled trial. Nutrition. 2013;29(9):1110-4. View abstract.

Cosmetic Ingredient Review Expert Panel. Final report on the safety assessment of AloeAndongensis Extract, Aloe Andongensis Leaf Juice,aloe Arborescens Leaf Extract, Aloe Arborescens Leaf Juice, Aloe Arborescens Leaf Protoplasts, Aloe Barbadensis Flower Extract, Aloe Barbadensis Leaf, Aloe Barbadensis Leaf Extract, Aloe Barbadensis Leaf Juice,aloe Barbadensis Leaf Polysaccharides, Aloe Barbadensis Leaf Water, Aloe Ferox Leaf Extract, Aloe Ferox Leaf Juice, and Aloe Ferox Leaf Juice Extract. Int J Toxicol 2007;26 Suppl 2:1-50. View abstract.

Bhalang K, Thunyakitpisal P, Rungsirisatean N. Acemannan, a polysaccharide extracted from Aloe vera, is effective in the treatment of oral aphthous ulceration. J Altern Complement Med 2013;19(5):429-34. View abstract.

Hajheydari Z, Saeedi M, Morteza-Semnani K, Soltani A. Effect of Aloe vera topical gel combined with tretinoin in treatment of mild and moderate acne vulgaris: a randomized, double-blind, prospective trial. J Dermatolog Treat 2014;25(2):123-9. View abstract.

Jiménez-Encarnación E, Ríos G, Muñoz-Mirabal A, Vilá LM. Euforia-induced acute hepatitis in a patient with scleroderma. BMJ Case Rep 2012;2012. View abstract.

Lee J, Lee MS, Nam KW. Acute toxic hepatitis caused by an aloe vera preparation in a young patient: a case report with a literature review. Korean J Gastroenterol 2014;64(1):54-8. View abstract.

López-Jornet P, Camacho-Alonso F, Molino-Pagan D. Prospective, randomized, double-blind, clinical evaluation of Aloe vera Barbadensis, applied in combination with a tongue protector to treat burning mouth syndrome. J Oral Pathol Med 2013;42(4):295-301. View abstract.

Molazem Z, Mohseni F, Younesi M, Keshavarzi S. Aloe vera gel and caesarean wound healing; a randomized controlled clinical trial. Glob J Health Sci 2014;7(1):203-9. View abstract.

Rahmani N, Khademloo M, Vosoughi K, Assadpour S. Effects of Aloe vera cream on chronic anal fissure pain, wound healing and hemorrhaging upon defection: a prospective double blind clinical trial. Eur Rev Med Pharmacol Sci 2014;18(7):1078-84. View abstract.

Reddy RL, Reddy RS, Ramesh T, Singh TR, Swapna LA, Laxmi NV. Randomized trial of aloe vera gel vs triamcinolone acetonide ointment in the treatment of oral lichen planus. Quintessence Int 2012;43(9):793-800. View abstract.

Sudarshan R, Annigeri RG, Sree Vijayabala G. Aloe vera in the treatment for oral submucous fibrosis - a preliminary study. J Oral Pathol Med 2012;41(10):755-61. View abstract.

Boudreau MD, Mellick PW, Olson GR, et al. Clear Evidence of Carcinogenic Activity by a Whole-Leaf Extract of Aloe barbadensis Miller (Aloe vera) in F344/N Rats. Toxicol Sci. 2013;131(1):26-39. View abstract.

Boudreau MD, Beland FA, Nichols JA, Pogribna M. Toxicology and carcinogenesis studies of a nondecolorized [corrected] whole leaf extract of Aloe barbadensis Miller (Aloe vera) in F344/N rats and B6C3F1 mice (drinking water study). Natl Toxicol Program Tech Rep Ser. 2013;(577):1-266. View abstract.

Guo X, Mei N. Aloe Vera - A Review of Toxicity and Adverse Clinical Effects. J Environ Sci Health C Environ Carcinog Ecotoxicol Rev 2016;34(2):77-96. View abstract.

International Agency for Research on Cancer (IARC). Aloe Vera. Some drugs and herbal products: IARC monographs on the evaluation of carcinogenic risks to humans, Volume 108. Lyon, France: International Agency for Research on Cancer; 2015. 37-71.

Sahebnasagh A, Ghasemi A, Akbari J, et al. Successful treatment of acute radiation proctitis with aloe vera: a preliminary randomized controlled clinical trial. J Altern Complement Med. 2017 Nov;23(11):858-65. View abstract.

Tanaka M, Yamamoto Y, Misawa E, et al. Effects of aloe sterol supplementation on skin elasticity, hydration, and collagen score: a 12-week double-blind, randomized, controlled trial. Skin Pharmacol Physiol. 2016;29(6):309-17. View abstract.

Zhang Y, Liu W, Liu D, Zhao T, Tian H. Efficacy of aloe vera supplementation on prediabetes and early non-treated diabetic patients: a systematic review and meta-analysis of randomized controlled trials. Nutrients 2016 Jun 23;8(7). View abstract.

Anuradha A, Patil B, Asha VR. Evaluation of efficacy of aloe vera in the treatment of oral submucous fibrosis - a clinical study. J Oral Pathol Med 2017 Jan;46(1):50-55. View abstract.

Dick WR, Fletcher EA, Shah SA. Reduction of fasting blood glucose and hemoglobin A1c using oral aloe vera: a meta-analysis. J Altern Complement Med. 2016 Jun;22(6):450-7. View abstract.

Suksombon N, Poolsup N, Punthanitisarn S. Effect of aloe vera on glycaemic control in prediabetes and type 2 diabetes: a systematic review and meta-analysis. J Clin Pharm Ther. 2016 Apr;41(2):180-8. View abstract.

Burusapat C, Supawan M, Pruksapong C, Pitiseree A, Suwantemee C. Topical aloe vera gel for accelerated wound healing of split-thickness skin graft donor sites: a double-blind, randomized, controlled trial and systematic review. Plast Reconstr Surg. 2018 Mar 30. doi: 10.1097/PRS.0000000000004515. View abstract.

Khorasani G1, Ahmadi A, Jalal Hosseinimehr S, Ahmadi A2, Taheri A, et al. The effects of aloe vera cream on split-thickness skin graft donor site management: a randomized, blinded, placebo-controlled study. Wounds. 2011 Feb;23(2):44-8. No doi. View abstract.

Hajhashemi M, Rafieian M, Rouhi Boroujeni HA, Miraj S, Memarian S, et al. The effect of Aloe vera gel and sweet almond oil on striae gravidarum in nulliparous women. J Matern Fetal Neonatal Med. 2018 Jul;31(13):1703-1708. doi: 10.1080/14767058.2017.1325865. View abstract.

Najafian Y, Khorasani ZM, Najafi MN, Hamedi SS, Mahjour M, Feyzabadi Z. Efficacy of Aloe vera/ Plantago major gel in diabetic foot ulcer: a randomized double-blind clinical trial. Curr Drug Discov Technol. 2018 Jan 14. doi: 10.2174/1570163815666180115093007. View abstract.

Hekmatpou D, Mehrabi F, Rahzani K, Aminiyan A. The effect of Aloe Vera gel on prevention of pressure ulcers in patients hospitalized in the orthopedic wards: a randomized triple-blind clinical trial. BMC Complement Altern Med 2018;18(1):264. doi: 10.1186/s12906-018-2326-2. View abstract.

Teplicki E, Ma Q, Castillo DE, et al. The effects of aloe vera on wound healing in cell proliferation, migration, and viability. Wounds 2018;30(9):263-8. View abstract.

Leng H, Pu L, Xu L, Shi X, Ji J, Chen K. Effects of aloe polysaccharide, a polysaccharide extracted from Aloe vera, on TNF-a-induced HaCaT cell proliferation and the underlying mechanism in psoriasis. Mol Med Rep 2018;18(3):3537-43. doi: 10.3892/mmr.2018.9319. View abstract.

Al-Maweri SA, Ashraf S, Lingam AS, et al. Aloe vera in treatment of oral submucous fibrosis: A systematic review and meta-analysis. J Oral Pathol Med. 2019;48(2):99-107. View abstract.

Kaminaka C, Yamamoto Y, Sakata M, et al. Effects of low-dose Aloe sterol supplementation on skin moisture, collagen score and objective or subjective symptoms: 12-week, double-blind, randomized controlled trial. J Dermatol. 2020. View abstract.

Sahebnasagh A, Ghasemi A, Akbari J, et al. Prevention of acute radiation-induced proctitis by Aloe vera: a prospective randomized, double-blind, placebo controlled clinical trial in pelvic cancer patients. BMC Complement Med Ther. 2020;20(1):146. View abstract.

Ahluwalia B, Magnusson MK, Böhn L, et al. Randomized clinical trial: Effects of Aloe barbadensis Mill. extract on symptoms, fecal microbiota and fecal metabolite profiles in patients with irritable bowel syndrome. Neurogastroenterol Motil. 2020;32(8):e13860. View abstract.

Koo HJ, Lee KR, Kim HS, Lee BM. Detoxification effects of aloe polysaccharide and propolis on the urinary excretion of metabolites in smokers. Food Chem Toxicol. 2019;130:99-108. View abstract.

Surakunprapha P, Winaikosol K, Chowchuen B, Punyavong P, Jenwitheesuk K, Jenwitheesuk K. A prospective randomized double-blind study of silicone gel plus herbal extracts versus placebo in pre-sternal hypertrophic scar prevention and amelioration. Heliyon. 2020;6(5):e03883. View abstract.

Alkhouli M, Laflouf M, Alhaddad M. Efficacy of Aloe-vera use for prevention of chemotherapy-induced oral mucositis in children with acute lymphoblastic leukemia: A randomized controlled clinical trial. Compr Child Adolesc Nurs. 2020:1-14. View abstract.

Leiva-Cala C, Lorenzo-Pouso AI, Centenera-Centenera B, et al. Clinical efficacy of an Aloe vera gel versus a 0.12% chlorhexidine gel in preventing traumatic ulcers in patients with fixed orthodontic appliances: a double-blind randomized clinical trial. Odontology. 2020;108(3):470-478. View abstract.

Kamath NP, Tandon S, Nayak R, Naidu S, Anand PS, Kamath YS. The effect of aloe vera and tea tree oil mouthwashes on the oral health of school children. Eur Arch Paediatr Dent. 2020;21(1):61-66. View abstract.

Hawrelak JA, Wohlmuth H, Pattinson M, et al. Western herbal medicines in the treatment of irritable bowel syndrome: A systematic review and meta-analysis. Complement Ther Med. 2020;48:102233. View abstract.

Størsrud S, Pontén I, Simrén M. A pilot study of the effect of Aloe barbadensis Mill. extract (AVH200®) in patients with irritable bowel syndrome: a randomized, double-blind, placebo-controlled study. J Gastrointestin Liver Dis 2015;24(3):275-80. View abstract.

Hutchings HA, Wareham K, Baxter JN, et al. A randomised, cross-over, placebo-controlled study of Aloe vera in patients with irritable bowel syndrome: effects on patient quality of life. ISRN Gastroenterol 2011;2011:206103. View abstract.

Davis K, Philpott S, Kumar D, Mendall M. Randomised double-blind placebo-controlled trial of aloe vera for irritable bowel syndrome. Int J Clin Pract 2006;60(9):1080-6. View abstract.

Shi Y, Wei K, Lu J, Wei J, Hu X, Chen T. A clinic trial evaluating the effects of Aloe vera fermentation gel on recurrent aphthous stomatitis. Can J Infect Dis Med Microbiol 2020;2020:8867548. View abstract.

Hoogenboom TCH, Patel N, Cook NA, Williams R, Taylor-Robinson SD, Lim AKP. The effect of Aloe vera juice on liver enzymes and hepatic structure in a healthy population. Integr Med (Encinitas) 2020;19(3):30-4. View abstract.

Poordast T, Ghaedian L, Ghaedian L, et al. Aloe vera; a new treatment for atrophic vaginitis, a randomized double-blinded controlled trial. J Ethnopharmacol 2020:113760. Online ahead of print. View abstract.

Panahi Y, Rastgar N, Zamani A, Sahebkar A. Comparing the Therapeutic Effects of Aloe vera and Olive Oil Combination Cream versus Topical Betamethasone for Atopic Dermatitis: A Randomized Double-blind Clinical Trial. J Pharmacopuncture. 2020;23(3):173-178. View abstract.

Mushtaq S, Mushtaq Z, Sarfraz J, et al. Comparison of effect of aloe vera gel with aspirin and celecoxib on platelet aggregation. Professional Med J. 2020; 27(5):973-978.

Badooei F, Imani E, Hosseini-Teshnizi S, Banar M, Memarzade M. Comparison of the effect of ginger and aloe vera mouthwashes on xerostomia in patients with type 2 diabetes: A clinical trial, triple-blind. Med Oral Patol Oral Cir Bucal 2021;26(4):e408-e413. View abstract.

Sahebnasagh A, Saghafi F, Ghasemi A, et al. Aloe vera for Prevention of Acute Radiation Proctitis in Colorectal Cancer a Preliminary Randomized, Placebo-Controlled Clinical Trial. J Gastrointest Cancer 2021. View abstract.

Ahluwalia B, Magnusson MK, Böhn L, et al. Aloe barbadensis Mill. extract improves symptoms in IBS patients with diarrhoea: post hoc analysis of two randomized double-blind controlled studies. Therap Adv Gastroenterol 2021;14:17562848211048133. View abstract.

Jadhav AN, Rathod SR, Kolte AP, Bawankar PV. Effect of Aloe vera as a local drug delivery agent in the management of periodontal diseases: A systematic review and meta-analysis. J Indian Soc Periodontol 2021;25(5):372-378. View abstract.

Hwang JH, Oh MR, Hwang JH, et al. Effect of processed aloe vera gel on immunogenicity in inactivated quadrivalent influenza vaccine and upper respiratory tract infection in healthy adults: A randomized double-blind placebo-controlled trial. Phytomedicine 2021;91:153668. View abstract.

Tateoka Y. Effectiveness of aloe fomentation for nipple-related complications during the early puerperium period: a randomized, controlled, interventional study. BMC Res Notes 2022;15(1):94. View abstract.

Bhatt G, Gupta S, Ghosh S. Comparative efficacy of topical aloe vera and low-level laser therapy in the management of oral lichen planus: a randomized clinical trial. Lasers Med Sci 2022;37(3):2063-2070. View abstract.

Fallahi M, Soroush A, Sadeghi N, Mansouri F, Mobaderi T, Mahdavikian S. Comparative Evaluation of the Effect of Aloe Vera Gel, Olive Oil, and Compound Aloe Vera Gel-Olive Oil on Prevention of Pressure Ulcer: A Randomized Controlled Trial. Adv Biomed Res 2022;11:6. View abstract.

Sharma S, Alfonso AR, Gordon AJ, Kwong J, Lin LJ, Chiu ES. Second-degree burns and Aloe vera: A meta-analysis and systematic review. Adv Skin Wound Care 2022;35(11):1-9. View abstract.

Levin NJ, Erben Y, Li Y, Brigham TJ, Bruce AJ. A systematic review and meta-analysis comparing burn healing outcomes between silver sulfadiazine and Aloe vera. Cureus 2022;14(10):e30815. View abstract.

Guberti M, Botti S, Caffarri C, et al. Efficacy and safety of a colostrum- and Aloe vera-based oral care protocol to prevent and treat severe oral mucositis in patients undergoing hematopoietic stem cell transplantation: a single-arm phase II study. Ann Hematol 2022;101(10):2325-2336. View abstract.

Mahboub M, Aghazadeh Attari AM, Sheikhalipour Z, et al. A comparative study of the impacts of Aloe vera gel and silver sulfadiazine cream 1% on healing, itching and pain of burn wounds: A randomized clinical trial. J Caring Sci 2021;11(3):132-138. View abstract.

Maleki A, Youseflu S. The effectiveness of Aloe vera on relief of irritation and nipple pain in lactating women: Systematic review and meta-analysis. Obstet Gynecol Int 2022;2022:7430581. View abstract.

Wang T, Liao J, Zheng L, Zhou Y, Jin Q, Wu Y. Aloe vera for prevention of radiation-induced dermatitis: A systematic review and cumulative analysis of randomized controlled trials. Front Pharmacol 2022;13:976698. View abstract.

Yousef NJ, Aljoujou AA, Mashlah AM, Hajeer MY. Assessment of the effectiveness of Aloe vera versus amlexanox in the treatment of recurrent aphthous ulcers: A three-arm placebo-controlled randomized clinical trial. Cureus 2022;14(10):e30693. View abstract.

Zou H, Liu Z, Wang Z, Fang J. Effects of Aloe vera in the treatment of oral ulcers: A systematic review and meta-analysis of randomised controlled trials. Oral Health Prev Dent 2022;20(1):509-516. View abstract.

Robijns J, Becherini C, Caini S, et al. Natural and miscellaneous agents for the prevention of acute radiation dermatitis: a systematic review and meta-analysis. Support Care Cancer 2023;31(3):195. View abstract.

Sahebnasagh M, Aksi V, Eslami F, et al. Prevention of radiotherapy-related oral mucositis with zinc and polyherbal mouthwash: a double-blind, randomized clinical trial. Eur J Med Res 2023;28(1):109. View abstract.

Leong XY, Gopinath D, Syeed SM, Veettil SK, Shetty NY, Menon RK. Comparative Efficacy and Safety of Interventions for the Treatment of Oral Lichen Planus: A Systematic Review and Network Meta-Analysis. J Clin Med 2023;12(8):2763. View abstract.

Widjaja SS, Sumantri IB, Rusdiana R, et al. Potential Benefits of Aloe vera and Raphanus sativus var. longipinnatus Gel for Prevention of Radiation-Induced Dermatitis in Head and Neck Cancer Patients. Iran J Pharm Res 2023;21(1):e132213. View abstract.

Sabbaghzadegan S, Soltani MH, Kamalinejad M, Bahrami M, Kabir A, Dadmehr M. The effect of a standardized capsule of Aloe vera gel on the quality of life in patients with systolic heart failure: A randomized double-blind placebo-controlled clinical trial. Phytother Res 2023;37(7):2800-2810. View abstract.

Lewis ED, Crowley DC, Guthrie N, Evans M. Healthy adults supplemented with a nutraceutical formulation containing Aloe vera gel, rosemary and Poria cocos enhances the effect of influenza vaccination in a randomized, triple-blind, placebo-controlled trial. Front Nutr. 2023;10:1116634. View abstract.

Rai A, Shrivastava PK, Kumar A, et al. Comparative effectiveness of medicinal interventions for oral submucous fibrosis: A network meta-analysis. J Stomatol Oral Maxillofac Surg 2023;124(3):101423. View abstract.