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Chitosan
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Gades MD, Stern JS. Chitosan supplementation does not affect fat absorption in healthy males fed a high-fat diet, a pilot study. Int J Obes 2002;26:119-22.. View abstract.
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Macchi G. A new approach to the treatment of obesity: Chitosan's effects on body weight reduction and plasma cholesterol levels. Acta Toxicol Ther 1996;17:303-20.
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Sciutto AM, Colombo P. Lipid-lowering effect of Chitosan dietary integrator and hypocaloric diet in obese subjects. Acta Toxicol Ther 1995;16:215-29.
10025
Veneroni G, Veneroni F, Contos S, et al. Effect of a new chitosan dietary integrator and hypocaloric diet on hyperlipidemia and overweight in obese patients. Acta Toxicol Ther 1996;17:53-70.
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Ylitalo R, Lehtinen S, Wuolijoki E, et al. Cholesterol-lowering properties and safety of chitosan. Arzneimittelforschung 2002;52:1-7.. View abstract.
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Metso S, Ylitalo R, Nikkila M, Wuolijoki E, et al. The effect of long-term microcrystalline chitosan therapy on plasma lipids and glucose concentrations in subjects with increased plasma total cholesterol: a randomised placebo-controlled double-blind crossover trial in healthy men and women. Eur J Clin Pharmacol 2003;59:741-6. View abstract.
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Gades MD, Stern JS. Chitosan supplementation and fat absorption in men and women. J Am Diet Assoc 2005;105:72-7. View abstract.
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Gallaher DD, Gallaher CM, Mahrt GJ, et al. A glucomannan and chitosan fiber supplement decreases plasma cholesterol and increases cholesterol excretion in overweight normocholesterolemic humans. J Am Coll Nutr 2002;21:428-33. View abstract.
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Bokura H, Kobayashi S. Chitosan decreases total cholesterol in women: a randomized, double-blind, placebo-controlled trial. Eur J Clin Nutr 2003;57:721-5. View abstract.
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Ni Mhurchu C, Dunshea-Mooij C, Bennett D, Rodgers A. Chitosan for overweight or obesity. Cochrane Database Syst Rev 2005;(3):CD003892. View abstract.
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Mhurchu CN, Poppitt SD, McGill AT, et al. The effect of the dietary supplement, Chitosan, on body weight: a randomised controlled trial in 250 overweight and obese adults. Int J Obes Relat Metab Disord 2004;28:1149-56. View abstract.
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Hayashi Y, Ohara N, Ganno T, et al. Chewing chitosan-containing gum effectively inhibits the growth of cariogenic bacteria. Arch Oral Biol 2007;52:290-4. View abstract.
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Tsai, G. J. and Su, W. H. Antibacterial activity of shrimp chitosan against Escherichia coli. J Food Prot. 1999;62(3):239-243. View abstract.
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Wuolijoki, E., Hirvela, T., and Ylitalo, P. Decrease in serum LDL cholesterol with microcrystalline chitosan. Methods Find.Exp Clin Pharmacol. 1999;21(5):357-361. View abstract.
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Tai TS, Sheu WH, Lee WJ, et al. Effect of chitosan on plasma lipoprotein concentrations in type 2 diabetic subjects with hypercholesterolemia. Diabetes Care 2000;23:1703-4. View abstract.
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Sano, H., Shibasaki, K., Matsukubo, T., and Takaesu, Y. Effect of chitosan rinsing on reduction of dental plaque formation. Bull.Tokyo Dent.Coll. 2003;44(1):9-16. View abstract.
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Deuchi, K., Kanauchi, O., Shizukuishi, M., and Kobayashi, E. Continuous and massive intake of chitosan affects mineral and fat- soluble vitamin status in rats fed on a high-fat diet. Biosci Biotechnol.Biochem 1995;59(7):1211-1216. View abstract.
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Kanauchi, O., Deuchi, K., Imasato, Y., Shizukuishi, M., and Kobayashi, E. Mechanism for the inhibition of fat digestion by chitosan and for the synergistic effect of ascorbate. Biosci.Biotechnol.Biochem 1995;59(5):786-790. View abstract.
41708
Shibasaki, K., Sano, H., Matsukubo, T., and Takaesu, Y. pH response of human dental plaque to chewing gum supplemented with low molecular chitosan. Bull Tokyo Dent Coll 1994;35(2):61-66. View abstract.
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Tarsi, R., Muzzarelli, R. A., Guzman, C. A., and Pruzzo, C. Inhibition of Streptococcus mutans adsorption to hydroxyapatite by low-molecular-weight chitosans. J Dent Res 1997;76(2):665-672. View abstract.
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Petronio, M. G., Mansi, A., Gallinelli, C., Pisani, S., Seganti, L., and Chiarini, F. In vitro effect of natural and semi-synthetic carbohydrate polymers on Chlamydia trachomatis infection. Chemotherapy 1997;43(3):211-217. View abstract.
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Girola M, De Bernardi M, and Contos S, et al. Dose effect in lipid-lowering activity of a new dietary integrator (chitosan, Garcinia cambogia extract, and chrome). Acta Toxicol Ther 1996;17:25-40.
41721
Veneroni G, Veneroni F, Contos S, and et al. Effect of new chitosan dietary integrator and hypocaloric diet on hyperlipidemia and overweight in obese patients. Acta Toxicol Ther 1996;17:53-70.
41722
Sciutto AM and Colombo P. Lipid-lowering effect of chitosan dietary integrator and hypocaloric diet in obese patients. Acta Toxicol Ther 1995;16:215-230.
41723
Macchi G. A new approach to the treatment of obesity: chitosan's effects on body weight reduction and plasma cholesterol levels. Acta Toxicol Ther 1996;17:303-320.
41724
Schiller RN, Barrager E, Schauss EA, and et al. A randomized, double-blind, placebo-controlled study examining the effects of a rapidly soluble chitosan dietary supplement on weight loss and body composition in overweight and mildly obese individuals. J Am Nutraceutical Assoc 2001;4(1):42-49.
41725
Koide, S. S. Chitin-chitosan: properties, benefits and risks. Nutrition Research 1998;8(6):1091-1101.
41726
Maezaki Y, Tsuji K, Nakawa, and et al. Hypocholesterolaemic effect of chitosan in adult males. Biosc Biochem Biotech 1993;57:1439-1444.
41729
Ernst E and Pitter MH. Chitosan as a treatment for body weight reduction? A meta-analysis. Perfusion 1998;11(11):461-465.
41730
Sano H, Shibasaki K Kaneko K and et al. Inhibitory effect of chitosan rinsing on plaque formation. J-Dent-Res 1998;77(March Special Issue A: Abstracts of papers):138 (Abs No 260).
92779
Akizawa T, Tsuruta Y, Okada Y, et al. Effect of chitosan chewing gum on reducing serum phosphorus in hemodialysis patients: a multi-center, randomized, double-blind, placebo-controlled trial. BMC Nephrol 2014;15:98. View abstract.
92780
Kubbinga M, Nguyen MA, Staubach P, et al. The influence of chitosan on the oral bioavailability of acyclovir-a comparative bioavailability study in humans. Pharm Res 2015;32(7):2241-9. View abstract.
92781
Jull AB, Ni Mhurchu C, Bennett DA, et al. Chitosan for overweight or obesity. Cochrane Database Syst Rev 2008;(3):CD003892. View abstract.
92782
Cheung RC, Ng TB, Wong JH, Chan WY. Chitosan: an update on potential biomedical and pharmaceutical applications. Mar Drugs 2015;13(8):5156-86. View abstract.
92783
Novak K, Cupp MJ, Tracy TS. Chapter 2: Chitosan. In: Dietary Supplements - Toxicology and Clinical Pharmacology. Cupp MJ, Tracy TS (Eds). Springer-Verlag New York, LLC. 2003:33-39.
92784
Savica V, Calo LA, Mondardo P, et al. Salivary phosphate-binding chewing gum reduces hyperphosphatemia in dialysis patients. J Am Soc Nephrol 2009;20(3):639-44. View abstract.
97706
Hernández-González SO, González-Ortiz M, Martínez-Abundis E, Robles-Cervantes JA. Chitosan improves insulin sensitivity as determined by the euglycemic-hyperinsulinemic clamp technique in obese subjects. Nutr Res. 2010;30(6):392-5. View abstract.
97707
Azad AK, Sermsintham N, Chandrkrachang S, Stevens WF. Chitosan membrane as a wound-healing dressing: characterization and clinical application. J Biomed Mater Res B Appl Biomater. 2004;69(2):216-22. View abstract.
97708
Allaert FA. Effect of NaCl + Chitosan 3% vs. NaCl on high blood pressure parameters of healthy volunteers with prehypertension. Minerva Cardioangiol. 2017;65(6):563-576. View abstract.
97709
Spigoni V, Aldigeri R, Antonini M, et al. Effects of a new nutraceutical formulation (berberine, red yeast rice and chitosan) on non-HDL cholesterol levels in individuals with dyslipidemia: Results from a randomized, double blind, placebo-controlled study. Int J Mol Sci. 2017;18(7). pii: E1498. View abstract.
97710
Schmidl D, Werkmeister R, Kaya S, et al. A Controlled, Randomized Double-Blind Study to Evaluate the Safety and Efficacy of Chitosan-N-Acetylcysteine for the Treatment of Dry Eye Syndrome. J Ocul Pharmacol Ther. 2017;33(5):375-382. View abstract.
97711
Dilokhuttakarn T, Vilai P, Rungsinaporn V. The efficacy of chitosan dressing in reducing blood loss for harvest site in split thickness skin graft: A randomized control trial. J Med Assoc Thai. 2016;99 Suppl 8:S19-S24. View abstract.
97712
Madrazo-Jiménez M, Rodríguez-Caballero Á, Serrera-Figallo MÁ, et al. The effects of a topical gel containing chitosan, 0,2% chlorhexidine, allantoin and despanthenol on the wound healing process subsequent to impacted lower third molar extraction. Med Oral Patol Oral Cir Bucal. 2016;21(6):e696-e702. View abstract.
97713
Valentine R, Athanasiadis T, Moratti S, Hanton L, Robinson S, Wormald PJ. The efficacy of a novel chitosan gel on hemostasis and wound healing after endoscopic sinus surgery. Am J Rhinol Allergy. 2010;24(1):70-5. View abstract.
97714
Zhou JC, Zhang JJ, Zhang W, Ke ZY, Zhang B. Efficacy of chitosan dressing on endoscopic sinus surgery: a systematic review and meta-analysis. Eur Arch Otorhinolaryngol. 2017;274(9):3269-3274. View abstract.
97715
Allaert FA. Double-blind, randomized, crossover, controlled clinical trial of NaCl + Chitosan 3% versus NaCl on mild or moderate high blood pressure during the diet and lifestyle improvement period before possible prescription of an antihypertensive treatment. Int Angiol. 2013;32(1):94-101. View abstract.
100170
Moraru C, Mincea MM, Frandes M, Timar B, Ostafe V. A meta-analysis on randomised controlled clinical trials evaluating the effect of the dietary supplement chitosan on weight loss, lipid parameters and blood pressure. Medicina (Kaunas). 2018;54(6):109. View abstract.
100171
Totsuka Sutto SE, Rodríguez Roldan YI, Cardona Muñoz EG, et al. Efficacy and safety of the combination of isosorbide dinitrate spray and chitosan gel for the treatment of diabetic foot ulcers: A double-blind, randomized, clinical trial. Diab Vasc Dis Res. 2018;15(4):348-351. View abstract.
106521
Vilasan A, Venkatesh PML, Varadhan KB, George JP, Dubey A. Comparative evaluation of chitosan chlorhexidine mouthwash in plaque control: a preliminary randomized controlled clinical trial. J Int Acad Periodontol 2020;22(3):166-73. View abstract.
112352
García MA, Hensler G, Al-Gousous J, Pielenhofer J, Wagner M, Lennernäs H, Langguth P. Novel food drug interaction mechanism involving acyclovir, chitosan and endogenous mucus. Drug Metab Pharmacokinet. 2023;49:100491. View abstract.