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Bilbao, I., Aguirre, A., Zabala, R., Gonzalez, R., Raton, J., and Diaz Perez, J. L. Allergic contact dermatitis from butoxyethyl nicotinic acid and Centella asiatica extract. Contact Dermatitis 1995;33(6):435-436. View abstract.

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Bradwejn J, Koszycki D, Shlik J, and et al. Centella asiatica decreases the acoustic startle response. 152nd Annual Meeting of the American Psychiatric Association, Washington DC, USA (May 15-20) 1999;

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Cesarone MR, Incandela L, De Sanctis MT, and et al. Evaluation of treatment of diabetic microangiopathy with total triterpenic fraction of Centella asiatica: a clinical prospective randomized trial with a microcirculatory model. Angiology 2001;52(10 suppl 2):S49-S54.

Incandela L, Belcaro G, De Sanctis MT, and et al. Total triterpenic fraction of Centella asiatica in the treatment of venous hypertension: a clinical, prospective, randomized trial using a combined microcirculatory model. Angiology 2001;52(10 suppl 2):S61-S67.

Incandela L, Belacaro G, Cesarone MR, and et al. Treatment of diabetic microangiopathy and edema with total triterpenic fraction of Centella asiatica: a prospective, placebo-controlled randomized study. Angiology 2001;52(10 suppl 2):S27-S31.

De Sanctis MT, Belcaro G, Incandela L, and et al. Treatment of edema and increased capillary filtration in venous hypertension with total triterpenic fraction of Centella asiatica: A clinical, prospective, placebo-controlled, randomized, dose-ranging trial. Angiology 2001;52(10 suppl 2):S55-S59.

Cesarone MR, Belcaro G, De Sanctis MT, and et al. Effects of the total triterpenic fraction of Centella asiatica in venous hypertensive microangiopathy: a prospective, placebo-controlled, randomized trial. Angiology 2001;52(10 suppl 2):S15-S18.

Cesarone MR, Belcaro G, Rulo A, and et al. Microcirculatory effects of total triterpenic fraction of Centella asiatica in chronic venous hypertension: measurement by laser Doppler, TcPo2-co2, and leg volumetry. Angiology 2001;52(10 suppl 2):S45-S48.

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Sarma DNK, Khosa RL, Chansauria JPN, and et al. Antistress activity of Tinospora cordifolia and Centella asiatica extracts. Phytotherapy Research 1996;10(2):181-189.

Klovekorn, W., Tepe, A., and Danesch, U. A randomized, double-blind, vehicle-controlled, half-side comparison with a herbal ointment containing Mahonia aquifolium, Viola tricolor and Centella asiatica for the treatment of mild-to-moderate atopic dermatitis. Int.J.Clin.Pharmacol.Ther. 2007;45(11):583-591. View abstract.

Dantuluri S, North-lewis P, Karthik SV. Gotu Kola induced hepatotoxicity in a child - need for caution with alternative remedies. Dig Liver Dis. 2011;43(6):500. View abstract.

García Hernández JÁ, Madera González D, Padilla Castillo M, Figueras Falcón T. Use of a specific anti-stretch mark cream for preventing or reducing the severity of striae gravidarum. Randomized, double-blind, controlled trial. Int J Cosmet Sci. 2013;35(3):233-7. View abstract.

Chandrika UG, Prasad kumarab PA. Gotu Kola (Centella asiatica): Nutritional Properties and Plausible Health Benefits. Adv Food Nutr Res. 2015;76:125-57. View abstract.

Chong NJ, Azziz Z. A systematic review on the chemical constituents of Centella asiatica. Res J Pharma Biol Chem Sci. 2011;2(3):445-459.

Saeidinia A, Keihanian F, Lashkari AP, et al. Partial-thickness burn wounds healing by topical treatment: a randomized controlled comparison between silver sulfadiazine and centiderm. Medicine (Baltimore). 2017 Mar;96(9):e6168. View abstract.

Muangman P, Praditsuktavorn B, Chinaroonchai K, Chuntrasakul C. Clinical efficacy test of polyester containing herbal extract dressings in burn wound healing. Int J Low Extrem Wounds. 2016 Sep;15(3):203-12. View abstract.

Belcaro G, Dugall M, Ippolito E, et al. Pycnogenol and centella asiatica to prevent asymptomatic atherosclerosis progression in clinical events. Minerva Cardioangiol. 2017 Feb;65(1):24-31. View abstract.

Luzzi R, Belcaro G, Ippolito E. Carotid plaque stabilization induced by the supplement association Pycnogenol and centella asiatica (Centellicum). Minerva Cardioangiol. 2016 Dec;64(6):603-9. View abstract.

Cotellese R, Hu S, Belcaro G, et al. Centella asiatica (Centellicum) facilitates the regular healing of surgical scars in subjects at high risk of keloids. Minerva Chir. 2018;73(2):151-156.

Hu S, Belcaro G, Hosoi M, Feragalli B, Luzzi R, Dugall M. Postpartum stretchmarks: repairing activity of an oral Centella asiatica supplementation (Centellicum®). Minerva Ginecol. 2018;70(5):629-634. View abstract.

Songvut P, Chariyavilaskul P, Tantisira MH, Khemawoot P. Safety and Pharmacokinetics of Standardized Extract of Centella asiatica (ECa 233) Capsules in Healthy Thai Volunteers: A Phase 1 Clinical Study. Planta Med. 2019;85(6):483-490. View abstract.

Thanthong S, Nanthong R, Kongwattanakul S, et al. Prophylaxis of radiation-induced dermatitis in patients with breast cancer using herbal creams: A prospective randomized controlled trial. Integr Cancer Ther. 2020;19:1534735420920714. View abstract.

Surakunprapha P, Winaikosol K, Chowchuen B, Punyavong P, Jenwitheesuk K, Jenwitheesuk K. A prospective randomized double-blind study of silicone gel plus herbal extracts versus placebo in pre-sternal hypertrophic scar prevention and amelioration. Heliyon. 2020;6(5):e03883. View abstract.

Damkerngsuntorn W, Rerknimitr P, Panchaprateep R, et al. The effects of a standardized extract of Centella asiatica on postlaser resurfacing wound healing on the face: A split-face, double-blind, randomized, placebo-controlled trial. J Altern Complement Med. 2020;26(6):529-536. View abstract.

Legiawati L, Bramono K, Indriatmi W, et al. Oral and topical Centella asiatica in type 2 diabetes mellitus patients with dry skin: A three-arm prospective randomized double-blind controlled trial. Evid Based Complement Alternat Med. 2020;2020:7253560. View abstract.

Astutik FEF, Fauzia Zuhroh D, Rizqi Lazuardi Ramadhan M. The effect of gotu kola (Centella asiatica L.) tea on blood pressure of hypertension. Enferm Clin. 2021;31 Suppl 2:S195-S198. View abstract.

Songvut P, Chariyavilaskul P, Khemawoot P, Tansawat R. Pharmacokinetics and metabolomics investigation of an orally modified formula of standardized Centella asiatica extract in healthy volunteers. Sci Rep. 2021;11(1):6850. View abstract.

Chiaretti M, Fegatelli DA, Ceccarelli G, Carru GA, Pappalardo G, Chiaretti AI. Comparison of flavonoids and Centella asiatica for the treatment of chronic anal fissure. A randomized clinical trial. Ann Ital Chir. 2018;89:330-336. View abstract.

Jana U, Sur TK, Maity LN, Debnath PK, Bhattacharyya D. A clinical study on the management of generalized anxiety disorder with Centella asiatica. Nepal Med Coll J. 2010 Mar;12(1):8-11. View abstract.

Puttarak P, Dilokthornsakul P, Saokaew S, et al. Effects of Centella asiatica (L.) Urb. on cognitive function and mood related outcomes: A systematic review and meta-analysis. Sci Rep. 2017;7(1):10646. View abstract.

Kuo YS, Chien HF, Lu W. Plectranthus amboinicus and Centella asiatica cream for the treatment of diabetic foot ulcers. Evid Based Complement Alternat Med. 2012;2012:418679. View abstract.

Chiaretti M, Fegatelli DA, Pappalardo G, Venti MDS, Chiaretti AI. Comparison of Centella with flavonoids for treatment of symptoms in hemorrhoidal disease and after surgical intervention: A Randomized Clinical Trial. Sci Rep. 2020;10(1):8009. View abstract.

Cesarone MR, Hu S, Belcaro G, et al. Pycnogenol®-Centellicum® supplementation improves lung fibrosis and post-COVID-19 lung healing. Minerva Med 2022;113(1):135-140. View abstract.

Anggraeni S, Umborowati MA, Damayanti D, Endaryanto A, Prakoeswa CRS. Role of Centella asiatica and ceramide in skin barrier improvement: a double blind clinical trial of Indonesian batik workers. J Basic Clin Physiol Pharmacol 2021;32(4):589-93. View abstract.

Wright KM, Bollen M, David J, et al. Pharmacokinetics and pharmacodynamics of key components of a standardized Centella asiatica product in cognitively impaired older adults: a phase 1, double-blind, randomized clinical trial. Antioxidants (Basel) 2022;11(2):215. View abstract.

Koonrungsesomboon N, Churyen A, Teekachunhatean S, Sangdee C, Hanprasertpong N. A Randomized Controlled Trial of Thai Medicinal Plant-4 Cream versus Diclofenac Gel in the Management of Symptomatic Osteoarthritis of the Knee. Evid Based Complement Alternat Med 2022;2022:8657000. View abstract.

Poomanee W, Yaowiwat N, Pattarachaidaecharuch T, Leelapornpisid P. Optimized multiherbal combination and in vivo anti-skin aging potential: a randomized double blind placebo controlled study. Sci Rep 2023;13(1):5633. View abstract.

Balevi M, Balevi A. The effect of Centella Asiatica cream on scar development in patients who underwent open carpal tunnel release surgery. J Hand Ther 2023. View abstract.