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Kamphuis MM, Lejeune MP, Saris WH, Westerterp-Plantenga MS. Effect of conjugated linoleic acid supplementation after weight loss on appetite and food intake in overweight subjects. Eur J Clin Nutr 2003;57:1268-74.. View abstract.

Wahle KW, Heys SD, Rotondo D. Conjugated linoleic acids: are they beneficial or detrimental to health? Prog Lipid Res 2004;43:553-87. View abstract.

Riserus U, Smedman A, Basu S, Vessby B. Metabolic effects of conjugated linoleic acid in humans: the Swedish experience. Am J Clin Nutr 2004;79(6 Suppl):1146S-8S. View abstract.

Larsson SC, Bergkvist L, Wolk A. High-fat dairy food and conjugated linoleic acid intakes in relation to colorectal cancer incidence in the Swedish Mammography Cohort. Am J Clin Nutr 2005;82:894-900. View abstract.

Diaz, M. L., Watkins, B. A., Li, Y., Anderson, R. A., and Campbell, W. W. Chromium picolinate and conjugated linoleic acid do not synergistically influence diet- and exercise-induced changes in body composition and health indexes in overweight women. J.Nutr.Biochem. 2008;19(1):61-68. View abstract.

Truitt, A., McNeill, G., and Vanderhoek, J. Y. Antiplatelet effects of conjugated linoleic acid isomers. Biochim.Biophys.Acta 5-18-1999;1438(2):239-246. View abstract.

Ip, M. M., Masso-Welch, P. A., Shoemaker, S. F., Shea-Eaton, W. K., and Ip, C. Conjugated linoleic acid inhibits proliferation and induces apoptosis of normal rat mammary epithelial cells in primary culture. Exp Cell Res 7-10-1999;250(1):22-34. View abstract.

Li, Y., Seifert, M. F., Ney, D. M., Grahn, M., Grant, A. L., Allen, K. G., and Watkins, B. A. Dietary conjugated linoleic acids alter serum IGF-I and IGF binding protein concentrations and reduce bone formation in rats fed (n-6) or (n-3) fatty acids. J Bone Miner.Res 1999;14(7):1153-1162. View abstract.

Yamasaki, M., Mansho, K., Mishima, H., Kasai, M., Sugano, M., Tachibana, H., and Yamada, K. Dietary effect of conjugated linoleic acid on lipid levels in white adipose tissue of Sprague-Dawley rats. Biosci.Biotechnol.Biochem. 1999;63(6):1104-1106. View abstract.

Matsuda, M. and DeFronzo, R. A. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999;22(9):1462-1470. View abstract.

Sakono, M., Miyanaga, F., Kawahara, S., Yamauchi, K., Fukuda, N., Watanabe, K., Iwata, T., and Sugano, M. Dietary conjugated linoleic acid reciprocally modifies ketogenesis and lipid secretion by the rat liver. Lipids 1999;34(9):997-1000. View abstract.

Basu, S., Smedman, A., and Vessby, B. Conjugated linoleic acid induces lipid peroxidation in humans. FEBS Lett. 2-18-2000;468(1):33-36. View abstract.

Hubbard, N. E., Lim, D., Summers, L., and Erickson, K. L. Reduction of murine mammary tumor metastasis by conjugated linoleic acid. Cancer Lett. 3-13-2000;150(1):93-100. View abstract.

Zambell, K. L., Keim, N. L., Van Loan, M. D., Gale, B., Benito, P., Kelley, D. S., and Nelson, G. J. Conjugated linoleic acid supplementation in humans: effects on body composition and energy expenditure. Lipids 2000;35(7):777-782. View abstract.

Tsuboyama-Kasaoka, N., Takahashi, M., Tanemura, K., Kim, H. J., Tange, T., Okuyama, H., Kasai, M., Ikemoto, S., and Ezaki, O. Conjugated linoleic acid supplementation reduces adipose tissue by apoptosis and develops lipodystrophy in mice. Diabetes 2000;49(9):1534-1542. View abstract.

McCarty, M. F. Activation of PPARgamma may mediate a portion of the anticancer activity of conjugated linoleic acid. Med Hypotheses 2000;55(3):187-188. View abstract.

Kelley, D. S., Taylor, P. C., Rudolph, I. L., Benito, P., Nelson, G. J., Mackey, B. E., and Erickson, K. L. Dietary conjugated linoleic acid did not alter immune status in young healthy women. Lipids 2000;35(10):1065-1071. View abstract.

Yamasaki, M., Kishihara, K., Mansho, K., Ogino, Y., Kasai, M., Sugano, M., Tachibana, H., and Yamada, K. Dietary conjugated linoleic acid increases immunoglobulin productivity of Sprague-Dawley rat spleen lymphocytes. Biosci.Biotechnol.Biochem. 2000;64(10):2159-2164. View abstract.

Ryder, J. W., Portocarrero, C. P., Song, X. M., Cui, L., Yu, M., Combatsiaris, T., Galuska, D., Bauman, D. E., Barbano, D. M., Charron, M. J., Zierath, J. R., and Houseknecht, K. L. Isomer-specific antidiabetic properties of conjugated linoleic acid. Improved glucose tolerance, skeletal muscle insulin action, and UCP-2 gene expression. Diabetes 2001;50(5):1149-1157. View abstract.

Benito, P., Nelson, G. J., Kelley, D. S., Bartolini, G., Schmidt, P. C., and Simon, V. The effect of conjugated linoleic acid on platelet function, platelet fatty acid composition, and blood coagulation in humans. Lipids 2001;36(3):221-227. View abstract.

Benito, P., Nelson, G. J., Kelley, D. S., Bartolini, G., Schmidt, P. C., and Simon, V. The effect of conjugated linoleic acid on plasma lipoproteins and tissue fatty acid composition in humans. Lipids 2001;36(3):229-236. View abstract.

Kimoto, N., Hirose, M., Futakuchi, M., Iwata, T., Kasai, M., and Shirai, T. Site-dependent modulating effects of conjugated fatty acids from safflower oil in a rat two-stage carcinogenesis model in female Sprague-Dawley rats. Cancer Lett. 7-10-2001;168(1):15-21. View abstract.

Pariza, M. W., Park, Y., and Cook, M. E. The biologically active isomers of conjugated linoleic acid. Prog Lipid Res 2001;40(4):283-298. View abstract.

Riserus, U., Berglund, L., and Vessby, B. Conjugated linoleic acid (CLA) reduced abdominal adipose tissue in obese middle-aged men with signs of the metabolic syndrome: a randomised controlled trial. Int J Obes.Relat Metab Disord 2001;25(8):1129-1135. View abstract.

Lin, Y., Schuurbiers, E., Van, der, V, and de Deckere, E. A. Conjugated linoleic acid isomers have differential effects on triglyceride secretion in Hep G2 cells. Biochim.Biophys Acta 8-29-2001;1533(1):38-46. View abstract.

Brown, J. M., Halvorsen, Y. D., Lea-Currie, Y. R., Geigerman, C., and McIntosh, M. Trans-10, cis-12, but not cis-9, trans-11, conjugated linoleic acid attenuates lipogenesis in primary cultures of stromal vascular cells from human adipose tissue. J Nutr 2001;131(9):2316-2321. View abstract.

Perseghin, G., Caumo, A., Caloni, M., Testolin, G., and Luzi, L. Incorporation of the fasting plasma FFA concentration into QUICKI improves its association with insulin sensitivity in nonobese individuals. J Clin.Endocrinol.Metab 2001;86(10):4776-4781. View abstract.

Palombo, J. D., Ganguly, A., Bistrian, B. R., and Menard, M. P. The antiproliferative effects of biologically active isomers of conjugated linoleic acid on human colorectal and prostatic cancer cells. Cancer Lett 3-28-2002;177(2):163-172. View abstract.

Meadus, W. J., MacInnis, R., and Dugan, M. E. Prolonged dietary treatment with conjugated linoleic acid stimulates porcine muscle peroxisome proliferator activated receptor gamma and glutamine-fructose aminotransferase gene expression in vivo. J Mol.Endocrinol. 2002;28(2):79-86. View abstract.

Liu, J., Chen, B., Liu, R., and Lu, G. [Inhibitory effect of conjugated linoleic acid on human gastric carcinoma cell line]. Wei Sheng Yan.Jiu. 1999;28(6):353-355. View abstract.

Chajes, V., Lavillonniere, F., Ferrari, P., Jourdan, M. L., Pinault, M., Maillard, V., Sebedio, J. L., and Bougnoux, P. Conjugated linoleic acid content in breast adipose tissue is not associated with the relative risk of breast cancer in a population of French patients. Cancer Epidemiol.Biomarkers Prev. 2002;11(7):672-673. View abstract.

Kim, E. J., Holthuizen, P. E., Park, H. S., Ha, Y. L., Jung, K. C., and Park, J. H. Trans-10,cis-12-conjugated linoleic acid inhibits Caco-2 colon cancer cell growth. Am J Physiol Gastrointest.Liver Physiol 2002;283(2):G357-G367. View abstract.

Kreider, R. B., Ferreira, M. P., Greenwood, M., Wilson, M., and Almada, A. L. Effects of conjugated linoleic acid supplementation during resistance training on body composition, bone density, strength, and selected hematological markers. J Strength.Cond.Res 2002;16(3):325-334. View abstract.

Noone, E. J., Roche, H. M., Nugent, A. P., and Gibney, M. J. The effect of dietary supplementation using isomeric blends of conjugated linoleic acid on lipid metabolism in healthy human subjects. Br J Nutr 2002;88(3):243-251. View abstract.

Voorrips, L. E., Brants, H. A., Kardinaal, A. F., Hiddink, G. J., van den Brandt, P. A., and Goldbohm, R. A. Intake of conjugated linoleic acid, fat, and other fatty acids in relation to postmenopausal breast cancer: the Netherlands Cohort Study on Diet and Cancer. Am J Clin Nutr 2002;76(4):873-882. View abstract.

Jung, M. Y. and Jung, M. O. Identification of conjugated linoleic acids in hydrogenated soybean oil by silver ion-impregnated HPLC and gas chromatography-ion impacted mass spectrometry of their 4,4-dimethyloxazoline derivatives. J Agric.Food Chem 10-9-2002;50(21):6188-6193. View abstract.

Rahman, S. M., Huda, M. N., Uddin, M. N., and Akhteruzzaman, S. Short-term administration of conjugated linoleic acid reduces liver triglyceride concentration and phosphatidate phosphohydrolase activity in OLETF rats. J Biochem.Mol.Biol 9-30-2002;35(5):494-497. View abstract.

Riserus, U., Basu, S., Jovinge, S., Fredrikson, G. N., Arnlov, J., and Vessby, B. Supplementation with conjugated linoleic acid causes isomer-dependent oxidative stress and elevated C-reactive protein: a potential link to fatty acid-induced insulin resistance. Circulation 10-8-2002;106(15):1925-1929. View abstract.

Takahashi, Y., Kushiro, M., Shinohara, K., and Ide, T. Dietary conjugated linoleic acid reduces body fat mass and affects gene expression of proteins regulating energy metabolism in mice. Comp Biochem.Physiol B Biochem.Mol.Biol 2002;133(3):395-404. View abstract.

Ostrowska, E., Cross, R. F., Muralitharan, M., Bauman, D. E., and Dunshea, F. R. Effects of dietary fat and conjugated linoleic acid on plasma metabolite concentrations and metabolic responses to homeostatic signals in pigs. Br J Nutr 2002;88(6):625-634. View abstract.

Miller, A., Stanton, C., and Devery, R. Cis 9, trans 11- and trans 10, cis 12-conjugated linoleic acid isomers induce apoptosis in cultured SW480 cells. Anticancer Res 2002;22(6C):3879-3887. View abstract.

Sher, J., Pronczuk, A., Hajri, T., and Hayes, K. C. Dietary conjugated linoleic acid lowers plasma cholesterol during cholesterol supplementation, but accentuates the atherogenic lipid profile during the acute phase response in hamsters. J Nutr 2003;133(2):456-460. View abstract.

Cho, H. J., Kim, W. K., Kim, E. J., Jung, K. C., Park, S., Lee, H. S., Tyner, A. L., and Park, J. H. Conjugated linoleic acid inhibits cell proliferation and ErbB3 signaling in HT-29 human colon cell line. Am J Physiol Gastrointest.Liver Physiol 2003;284(6):G996-1005. View abstract.

Xu, X., Storkson, J., Kim, S., Sugimoto, K., Park, Y., and Pariza, M. W. Short-term intake of conjugated linoleic acid inhibits lipoprotein lipase and glucose metabolism but does not enhance lipolysis in mouse adipose tissue. J Nutr 2003;133(3):663-667. View abstract.

Albers, R., van der Wielen, R. P., Brink, E. J., Hendriks, H. F., Dorovska-Taran, V. N., and Mohede, I. C. Effects of cis-9, trans-11 and trans-10, cis-12 conjugated linoleic acid (CLA) isomers on immune function in healthy men. Eur J Clin Nutr 2003;57(4):595-603. View abstract.

Brown, J. M., Boysen, M. S., Jensen, S. S., Morrison, R. F., Storkson, J., Lea-Currie, R., Pariza, M., Mandrup, S., and McIntosh, M. K. Isomer-specific regulation of metabolism and PPARgamma signaling by CLA in human preadipocytes. J Lipid Res 2003;44(7):1287-1300. View abstract.

Ma, D. W., Field, C. J., and Clandinin, M. T. An enriched mixture of trans-10,cis-12-CLA inhibits linoleic acid metabolism and PGE2 synthesis in MDA-MB-231 cells. Nutr Cancer 2002;44(2):203-212. View abstract.

Nagao, K., Inoue, N., Wang, Y. M., Hirata, J., Shimada, Y., Nagao, T., Matsui, T., and Yanagita, T. The 10trans,12cis isomer of conjugated linoleic acid suppresses the development of hypertension in Otsuka Long-Evans Tokushima fatty rats. Biochem.Biophys.Res Commun. 6-20-2003;306(1):134-138. View abstract.

Kamphuis, M. M., Lejeune, M. P., Saris, W. H., and Westerterp-Plantenga, M. S. The effect of conjugated linoleic acid supplementation after weight loss on body weight regain, body composition, and resting metabolic rate in overweight subjects. Int J Obes Relat Metab Disord 2003;27(7):840-847. View abstract.

Politis, I., Dimopoulou, M., Voudouri, A., Noikokyris, P., and Feggeros, K. Effects of dietary conjugated linoleic acid isomers on several functional properties of macrophages and heterophils in laying hens. Br Poult.Sci 2003;44(2):203-210. View abstract.

Kim, E. J., Kang, I. J., Cho, H. J., Kim, W. K., Ha, Y. L., and Park, J. H. Conjugated linoleic acid downregulates insulin-like growth factor-I receptor levels in HT-29 human colon cancer cells. J Nutr 2003;133(8):2675-2681. View abstract.

Steinhart, H., Rickert, R., and Winkler, K. Identification and analysis of conjugated linoleic acid isomers (CLA). Eur.J Med Res 8-20-2003;8(8):370-372. View abstract.

Larsen, T. M., Toubro, S., and Astrup, A. Efficacy and safety of dietary supplements containing CLA for the treatment of obesity: evidence from animal and human studies. J Lipid Res 2003;44(12):2234-2241. View abstract.

Oikawa, D., Nakanishi, T., Nakamura, Y., Takahashi, Y., Yamamoto, T., Shiba, N., Tobisa, M., Takagi, T., Iwamoto, H., Tachibana, T., and Furuse, M. Dietary CLA and DHA modify skin properties in mice. Lipids 2003;38(6):609-614. View abstract.

Shultz, T. D., Chew, B. P., and Seaman, W. R. Differential stimulatory and inhibitory responses of human MCF-7 breast cancer cells to linoleic acid and conjugated linoleic acid in culture. Anticancer Res 1992;12(6B):2143-2145. View abstract.

Kelly, O., Cusack, S., Jewell, C., and Cashman, K. D. The effect of polyunsaturated fatty acids, including conjugated linoleic acid, on calcium absorption and bone metabolism and composition in young growing rats. Br J Nutr 2003;90(4):743-750. View abstract.

Petridou, A., Mougios, V., and Sagredos, A. Supplementation with CLA: isomer incorporation into serum lipids and effect on body fat of women. Lipids 2003;38(8):805-811. View abstract.

Cho, H. J., Lee, H. S., Chung, C. K., Kang, Y. H., Ha, Y. L., Park, H. S., and Park, J. H. trans-10, cis-12 conjugated linoleic acid reduces insulin-like growth factor-II secretion in HT-29 human colon cancer cells. J Med Food 2003;6(3):193-199. View abstract.

Sneddon, A. A., Wu, H. C., Farquharson, A., Grant, I., Arthur, J. R., Rotondo, D., Choe, S. N., and Wahle, K. W. Regulation of selenoprotein GPx4 expression and activity in human endothelial cells by fatty acids, cytokines and antioxidants. Atherosclerosis 2003;171(1):57-65. View abstract.

Valeille, K., Gripois, D., Blouquit, M. F., Souidi, M., Riottot, M., Bouthegourd, J. C., Serougne, C., and Martin, J. C. Lipid atherogenic risk markers can be more favourably influenced by the cis-9,trans-11-octadecadienoate isomer than a conjugated linoleic acid mixture or fish oil in hamsters. Br J Nutr 2004;91(2):191-199. View abstract.

Lenz, T. L. and Hamilton, W. R. Supplemental products used for weight loss. J Am Pharm Assoc (Wash.DC.) 2004;44(1):59-67. View abstract.

Oh, Y. S., Lee, H. S., Cho, H. J., Lee, S. G., Jung, K. C., and Park, J. H. Conjugated linoleic acid inhibits DNA synthesis and induces apoptosis in TSU-Pr1 human bladder cancer cells. Anticancer Res 2003;23(6C):4765-4772. View abstract.

Tanmahasamut, P., Liu, J., Hendry, L. B., and Sidell, N. Conjugated linoleic acid blocks estrogen signaling in human breast cancer cells. J Nutr 2004;134(3):674-680. View abstract.

McNeel, R. L., Smith, E. O., and Mersmann, H. J. Isomers of conjugated linoleic acid modulate human preadipocyte differentiation. In Vitro Cell Dev Biol Anim 2003;39(8-9):375-382. View abstract.

Brown, J. M., Boysen, M. S., Chung, S., Fabiyi, O., Morrison, R. F., Mandrup, S., and McIntosh, M. K. Conjugated linoleic acid induces human adipocyte delipidation: autocrine/paracrine regulation of MEK/ERK signaling by adipocytokines. J Biol Chem 6-18-2004;279(25):26735-26747. View abstract.

Park, H. S., Cho, H. Y., Ha, Y. L., and Park, J. H. Dietary conjugated linoleic acid increases the mRNA ratio of Bax/Bcl-2 in the colonic mucosa of rats. J Nutr Biochem. 2004;15(4):229-235. View abstract.

Malpuech-Brugere, C., Verboeket-van de Venne WP, Mensink, R. P., Arnal, M. A., Morio, B., Brandolini, M., Saebo, A., Lassel, T. S., Chardigny, J. M., Sebedio, J. L., and Beaufrere, B. Effects of two conjugated linoleic Acid isomers on body fat mass in overweight humans. Obes Res 2004;12(4):591-598. View abstract.

Eyjolfson, V., Spriet, L. L., and Dyck, D. J. Conjugated linoleic acid improves insulin sensitivity in young, sedentary humans. Med Sci Sports Exerc. 2004;36(5):814-820. View abstract.

Yamasaki, M., Kitagawa, T., Chujo, H., Koyanagi, N., Nishida, E., Nakaya, M., Yoshimi, K., Maeda, H., Nou, S., Iwata, T., Ogita, K., Tachibana, H., and Yamada, K. Physiological difference between free and triglyceride-type conjugated linoleic acid on the immune function of C57BL/6N mice. J Agric.Food Chem 6-2-2004;52(11):3644-3648. View abstract.

Riserus, U., Vessby, B., Arnlov, J., and Basu, S. Effects of cis-9,trans-11 conjugated linoleic acid supplementation on insulin sensitivity, lipid peroxidation, and proinflammatory markers in obese men. Am J Clin Nutr 2004;80(2):279-283. View abstract.

Tricon, S., Burdge, G. C., Kew, S., Banerjee, T., Russell, J. J., Jones, E. L., Grimble, R. F., Williams, C. M., Yaqoob, P., and Calder, P. C. Opposing effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on blood lipids in healthy humans. Am J Clin Nutr 2004;80(3):614-620. View abstract.

Inoue, N., Nagao, K., Hirata, J., Wang, Y. M., and Yanagita, T. Conjugated linoleic acid prevents the development of essential hypertension in spontaneously hypertensive rats. Biochem.Biophys.Res.Commun. 10-15-2004;323(2):679-684. View abstract.

Kelly, O. and Cashman, K. D. The effect of conjugated linoleic acid on calcium absorption and bone metabolism and composition in adult ovariectomised rats. Prostaglandins Leukot.Essent.Fatty Acids 2004;71(5):295-301. View abstract.

Moloney, F., Yeow, T. P., Mullen, A., Nolan, J. J., and Roche, H. M. Conjugated linoleic acid supplementation, insulin sensitivity, and lipoprotein metabolism in patients with type 2 diabetes mellitus. Am J Clin Nutr 2004;80(4):887-895. View abstract.

Song, H. J., Sneddon, A. A., Barker, P. A., Bestwick, C., Choe, S. N., McClinton, S., Grant, I., Rotondo, D., Heys, S. D., and Wahle, K. W. Conjugated linoleic acid inhibits proliferation and modulates protein kinase C isoforms in human prostate cancer cells. Nutr Cancer 2004;49(1):100-108. View abstract.

Hargrave, K. M., Meyer, B. J., Li, C., Azain, M. J., Baile, C. A., and Miner, J. L. Influence of dietary conjugated linoleic Acid and fat source on body fat and apoptosis in mice. Obes Res 2004;12(9):1435-1444. View abstract.

Choi, J. S., Jung, M. H., Park, H. S., and Song, J. Effect of conjugated linoleic acid isomers on insulin resistance and mRNA levels of genes regulating energy metabolism in high-fat-fed rats. Nutrition 2004;20(11-12):1008-1017. View abstract.

Tricon, S., Burdge, G. C., Kew, S., Banerjee, T., Russell, J. J., Grimble, R. F., Williams, C. M., Calder, P. C., and Yaqoob, P. Effects of cis-9,trans-11 and trans-10,cis-12 conjugated linoleic acid on immune cell function in healthy humans. Am J Clin Nutr 2004;80(6):1626-1633. View abstract.

Cusack, S., Jewell, C., and Cashman, K. D. The effect of conjugated linoleic acid on the viability and metabolism of human osteoblast-like cells. Prostaglandins Leukot.Essent.Fatty Acids 2005;72(1):29-39. View abstract.

Nagao, K., Inoue, N., Wang, Y. M., Shirouchi, B., and Yanagita, T. Dietary conjugated linoleic acid alleviates nonalcoholic fatty liver disease in Zucker (fa/fa) rats. J.Nutr. 2005;135(1):9-13. View abstract.

Shultz, T. D., Chew, B. P., Seaman, W. R., and Luedecke, L. O. Inhibitory effect of conjugated dienoic derivatives of linoleic acid and beta-carotene on the in vitro growth of human cancer cells. Cancer Lett 4-15-1992;63(2):125-133. View abstract.

Changhua, L., Jindong, Y., Defa, L., Lidan, Z., Shiyan, Q., and Jianjun, X. Conjugated linoleic acid attenuates the production and gene expression of proinflammatory cytokines in weaned pigs challenged with lipopolysaccharide. J Nutr 2005;135(2):239-244. View abstract.

Kim, J. H., Hubbard, N. E., Ziboh, V., and Erickson, K. L. Conjugated linoleic acid reduction of murine mammary tumor cell growth through 5-hydroxyeicosatetraenoic acid. Biochim.Biophys Acta 2-21-2005;1687(1-3):103-109. View abstract.

Chung, S., Brown, J. M., Sandberg, M. B., and McIntosh, M. Trans-10,cis-12 CLA increases adipocyte lipolysis and alters lipid droplet-associated proteins: role of mTOR and ERK signaling. J Lipid Res 2005;46(5):885-895. View abstract.

Gaullier, J. M., Halse, J., Hoye, K., Kristiansen, K., Fagertun, H., Vik, H., and Gudmundsen, O. Supplementation with conjugated linoleic acid for 24 months is well tolerated by and reduces body fat mass in healthy, overweight humans. J Nutr 2005;135(4):778-784. View abstract.

Nugent, A. P., Roche, H. M., Noone, E. J., Long, A., Kelleher, D. K., and Gibney, M. J. The effects of conjugated linoleic acid supplementation on immune function in healthy volunteers. Eur.J Clin Nutr 2005;59(6):742-750. View abstract.

Kloss, R., Linscheid, J., Johnson, A., Lawson, B., Edwards, K., Linder, T., Stocker, K., Petitte, J., and Kern, M. Effects of conjugated linoleic acid supplementation on blood lipids and adiposity of rats fed diets rich in saturated versus unsaturated fat. Pharmacol.Res 2005;51(6):503-507. View abstract.

Pal, S., Takechi, R., and Ho, S. S. Conjugated linoleic acid suppresses the secretion of atherogenic lipoproteins from human HepG2 liver cells. Clin Chem Lab Med 2005;43(3):269-274. View abstract.

Kim, H. K., Kim, S. R., Ahn, J. Y., Cho, I. J., Yoon, C. S., and Ha, T. Y. Dietary conjugated linoleic acid reduces lipid peroxidation by increasing oxidative stability in rats. J Nutr Sci Vitaminol.(Tokyo) 2005;51(1):8-15. View abstract.

Brownbill, R. A., Petrosian, M., and Ilich, J. Z. Association between dietary conjugated linoleic acid and bone mineral density in postmenopausal women. J Am Coll Nutr 2005;24(3):177-181. View abstract.

Cimini, A., Cristiano, L., Colafarina, S., Benedetti, E., Di Loreto, S., Festuccia, C., Amicarelli, F., Canuto, R. A., and Ceru, M. P. PPARgamma-dependent effects of conjugated linoleic acid on the human glioblastoma cell line (ADF). Int J Cancer 12-20-2005;117(6):923-933. View abstract.

Lock, A. L., Horne, C. A., Bauman, D. E., and Salter, A. M. Butter naturally enriched in conjugated linoleic acid and vaccenic acid alters tissue fatty acids and improves the plasma lipoprotein profile in cholesterol-fed hamsters. J Nutr 2005;135(8):1934-1939. View abstract.

Desroches, S., Chouinard, P. Y., Galibois, I., Corneau, L., Delisle, J., Lamarche, B., Couture, P., and Bergeron, N. Lack of effect of dietary conjugated linoleic acids naturally incorporated into butter on the lipid profile and body composition of overweight and obese men. Am J Clin Nutr 2005;82(2):309-319. View abstract.

Kuniyasu, H., Yoshida, K., Sasaki, T., Sasahira, T., Fujii, K., and Ohmori, H. Conjugated linoleic acid inhibits peritoneal metastasis in human gastrointestinal cancer cells. Int J Cancer 2-1-2006;118(3):571-576. View abstract.

Lee, J. H., Cho, K. H., Lee, K. T., and Kim, M. R. Antiatherogenic effects of structured lipid containing conjugated linoleic acid in C57BL/6J mice. J Agric.Food Chem 9-7-2005;53(18):7295-7301. View abstract.

Kim, J. H., Hubbard, N. E., Ziboh, V., and Erickson, K. L. Attenuation of breast tumor cell growth by conjugated linoleic acid via inhibition of 5-lipoxygenase activating protein. Biochim.Biophys Acta 10-1-2005;1736(3):244-250. View abstract.

Herrera, J. A., Shahabuddin, A. K., Ersheng, G., Wei, Y., Garcia, R. G., and Lopez-Jaramillo, P. Calcium plus linoleic acid therapy for pregnancy-induced hypertension. Int J Gynaecol Obstet 2005;91(3):221-227. View abstract.

Muller, A., Ringseis, R., Dusterloh, K., Gahler, S., Eder, K., and Steinhart, H. Detection of conjugated dienoic fatty acids in human vascular smooth muscle cells treated with conjugated linoleic acid. Biochim.Biophys Acta 12-15-2005;1737(2-3):145-151. View abstract.

Lee, S. H., Yamaguchi, K., Kim, J. S., Eling, T. E., Safe, S., Park, Y., and Baek, S. J. Conjugated linoleic acid stimulates an anti-tumorigenic protein NAG-1 in an isomer specific manner. Carcinogenesis 2006;27(5):972-981. View abstract.

Naumann, E., Carpentier, Y. A., Saebo, A., Lassel, T. S., Chardigny, J. M., Sebedio, J. L., and Mensink, R. P. Cis-9, trans- 11 and trans-10, cis-12 conjugated linoleic acid (CLA) do not affect the plasma lipoprotein profile in moderately overweight subjects with LDL phenotype B. Atherosclerosis 2006;188(1):167-174. View abstract.

De La, Torre A., Debiton, E., Durand, D., Chardigny, J. M., Berdeaux, O., Loreau, O., Barthomeuf, C., Bauchart, D., and Gruffat, D. Conjugated linoleic acid isomers and their conjugated derivatives inhibit growth of human cancer cell lines. Anticancer Res 2005;25(6B):3943-3949. View abstract.

Taylor, J. S., Williams, S. R., Rhys, R., James, P., and Frenneaux, M. P. Conjugated linoleic acid impairs endothelial function. Arterioscler.Thromb.Vasc.Biol 2006;26(2):307-312. View abstract.

Zhao, L., Yin, J., Li, D., Lai, C., Chen, X., and Ma, D. Conjugated linoleic acid can prevent tumor necrosis factor gene expression by inhibiting nuclear factor binding activity in peripheral blood mononuclear cells from weaned pigs challenged with lipopolysaccharide. Arch Anim Nutr 2005;59(6):429-438. View abstract.

Wang, L. S., Huang, Y. W., Sugimoto, Y., Liu, S., Chang, H. L., Ye, W., Shu, S., and Lin, Y. C. Conjugated linoleic acid (CLA) up-regulates the estrogen-regulated cancer suppressor gene, protein tyrosine phosphatase gamma (PTPgama), in human breast cells. Anticancer Res 2006;26(1A):27-34. View abstract.

Song, H. J., Sneddon, A. A., Heys, S. D., and Wahle, K. W. Induction of apoptosis and inhibition of NF-kappaB activation in human prostate cancer cells by the cis-9, trans-11 but not the trans-10, cis-12 isomer of conjugated linoleic acid. Prostate 6-1-2006;66(8):839-846. View abstract.

Larsen, T. M., Toubro, S., Gudmundsen, O., and Astrup, A. Conjugated linoleic acid supplementation for 1 y does not prevent weight or body fat regain. Am J Clin Nutr 2006;83(3):606-612. View abstract.

Pinkoski, C., Chilibeck, P. D., Candow, D. G., Esliger, D., Ewaschuk, J. B., Facci, M., Farthing, J. P., and Zello, G. A. The effects of conjugated linoleic acid supplementation during resistance training. Med Sci Sports Exerc. 2006;38(2):339-348. View abstract.

Raff, M., Tholstrup, T., Sejrsen, K., Straarup, E. M., and Wiinberg, N. Diets rich in conjugated linoleic acid and vaccenic acid have no effect on blood pressure and isobaric arterial elasticity in healthy young men. J Nutr 2006;136(4):992-997. View abstract.

Ringseis, R., Muller, A., Dusterloh, K., Schleser, S., Eder, K., and Steinhart, H. Formation of conjugated linoleic acid metabolites in human vascular endothelial cells. Biochim.Biophys Acta 2006;1761(3):377-383. View abstract.

Park, H. S., Chun, C. S., Kim, S., Ha, Y. L., and Park, J. H. Dietary trans-10, cis-12 and cis-9,trans-11 Conjugated Linoleic Acids Induce Apoptosis in the Colonic Mucosa of Rats Treated with 1,2-Dimethylhydrazine. J Med Food 2006;9(1):22-27. View abstract.

Herrera, J. A., Arevalo-Herrera, M., Shahabuddin, A. K., Ersheng, G., Herrera, S., Garcia, R. G., and Lopez-Jaramillo, P. Calcium and conjugated linoleic acid reduces pregnancy-induced hypertension and decreases intracellular calcium in lymphocytes. Am.J.Hypertens. 2006;19(4):381-387. View abstract.

Wang, L. S., Huang, Y. W., Liu, S., Chang, H. L., Ye, W., Shu, S., Sugimoto, Y., Funk, J. A., Smeaks, D. D., Hill, L. N., and Lin, Y. C. Conjugated linoleic acid (CLA) modulates prostaglandin E2 (PGE2) signaling in canine mammary cells. Anticancer Res 2006;26(2A):889-898. View abstract.

Watras, A. C., Buchholz, A. C., Close, R. N., Zhang, Z., and Schoeller, D. A. The role of conjugated linoleic acid in reducing body fat and preventing holiday weight gain. Int.J.Obes.(Lond) 2007;31(3):481-487. View abstract.

Rahman, M. M., Bhattacharya, A., Banu, J., and Fernandes, G. Conjugated linoleic acid protects against age-associated bone loss in C57BL/6 female mice. J Nutr Biochem. 2007;18(7):467-474. View abstract.

Syvertsen, C., Halse, J., Hoivik, H. O., Gaullier, J. M., Nurminiemi, M., Kristiansen, K., Einerhand, A., O'Shea, M., and Gudmundsen, O. The effect of 6 months supplementation with conjugated linoleic acid on insulin resistance in overweight and obese. Int.J.Obes.(Lond) 2007;31(7):1148-1154. View abstract.

Purushotham, A., Wendel, A. A., Liu, L. F., and Belury, M. A. Maintenance of adiponectin attenuates insulin resistance induced by dietary conjugated linoleic acid in mice. J Lipid Res 2007;48(2):444-452. View abstract.

Colakoglu, S., Colakoglu, M., Taneli, F., Cetinoz, F., and Turkmen, M. Cumulative effects of conjugated linoleic acid and exercise on endurance development, body composition, serum leptin and insulin levels. J.Sports Med.Phys.Fitness 2006;46(4):570-577. View abstract.

Kang, J. H., Lee, G. S., Jeung, E. B., and Yang, M. P. Trans-10, cis-12-conjugated linoleic acid increases phagocytosis of porcine peripheral blood polymorphonuclear cells in vitro. Br.J Nutr 2007;97(1):117-125. View abstract.

Platt, I., Rao, L. G., and El Sohemy, A. Isomer-specific effects of conjugated linoleic acid on mineralized bone nodule formation from human osteoblast-like cells. Exp.Biol.Med (Maywood.) 2007;232(2):246-252. View abstract.

Nazare, J. A., de la Perriere, A. B., Bonnet, F., Desage, M., Peyrat, J., Maitrepierre, C., Louche-Pelissier, C., Bruzeau, J., Goudable, J., Lassel, T., Vidal, H., and Laville, M. Daily intake of conjugated linoleic acid-enriched yoghurts: effects on energy metabolism and adipose tissue gene expression in healthy subjects. Br.J Nutr 2007;97(2):273-280. View abstract.

Gaullier, J. M., Halse, J., Hoivik, H. O., Hoye, K., Syvertsen, C., Nurminiemi, M., Hassfeld, C., Einerhand, A., O'Shea, M., and Gudmundsen, O. Six months supplementation with conjugated linoleic acid induces regional-specific fat mass decreases in overweight and obese. Br.J Nutr 2007;97(3):550-560. View abstract.

Perez-Matute, P., Marti, A., Martinez, J. A., Fernandez-Otero, M. P., Stanhope, K. L., Havel, P. J., and Moreno-Aliaga, M. J. Conjugated linoleic acid inhibits glucose metabolism, leptin and adiponectin secretion in primary cultured rat adipocytes. Mol.Cell Endocrinol. 3-30-2007;268(1-2):50-58. View abstract.

Purushotham, A., Shrode, G. E., Wendel, A. A., Liu, L. F., and Belury, M. A. Conjugated linoleic acid does not reduce body fat but decreases hepatic steatosis in adult Wistar rats. J Nutr Biochem. 2007;18(10):676-684. View abstract.

Fischer-Posovszky, P., Kukulus, V., Zulet, M. A., Debatin, K. M., and Wabitsch, M. Conjugated linoleic acids promote human fat cell apoptosis. Horm.Metab Res 2007;39(3):186-191. View abstract.

Lambert, E. V., Goedecke, J. H., Bluett, K., Heggie, K., Claassen, A., Rae, D. E., West, S., Dugas, J., Dugas, L., Meltzeri, S., Charlton, K., and Mohede, I. Conjugated linoleic acid versus high-oleic acid sunflower oil: effects on energy metabolism, glucose tolerance, blood lipids, appetite and body composition in regularly exercising individuals. Br.J Nutr 2007;97(5):1001-1011. View abstract.

Storey, A., Rogers, J. S., McArdle, F., Jackson, M. J., and Rhodes, L. E. Conjugated linoleic acids modulate UVR-induced IL-8 and PGE2 in human skin cells: potential of CLA isomers in nutritional photoprotection. Carcinogenesis 2007;28(6):1329-1333. View abstract.

Ou, L., Ip, C., Lisafeld, B., and Ip, M. M. Conjugated linoleic acid induces apoptosis of murine mammary tumor cells via Bcl-2 loss. Biochem.Biophys.Res Commun. 5-18-2007;356(4):1044-1049. View abstract.

Choi, J. S., Koh, I. U., Jung, M. H., and Song, J. Effects of three different conjugated linoleic acid preparations on insulin signalling, fat oxidation and mitochondrial function in rats fed a high-fat diet. Br.J Nutr 2007;98(2):264-275. View abstract.

Cherian, G., Traber, M. G., Goeger, M. P., and Leonard, S. W. Conjugated linoleic acid and fish oil in laying hen diets: effects on egg fatty acids, thiobarbituric acid reactive substances, and tocopherols during storage. Poult.Sci 2007;86(5):953-958. View abstract.

Steck, S. E., Chalecki, A. M., Miller, P., Conway, J., Austin, G. L., Hardin, J. W., Albright, C. D., and Thuillier, P. Conjugated linoleic acid supplementation for twelve weeks increases lean body mass in obese humans. J Nutr 2007;137(5):1188-1193. View abstract.

Cao, Z. P., Wang, F., Xiang, X. S., Cao, R., Zhang, W. B., and Gao, S. B. Intracerebroventricular administration of conjugated linoleic acid (CLA) inhibits food intake by decreasing gene expression of NPY and AgRP. Neurosci.Lett. 5-18-2007;418(3):217-221. View abstract.

Rossary, A., Arab, K., and Steghens, J. P. Polyunsaturated fatty acids modulate NOX 4 anion superoxide production in human fibroblasts. Biochem.J 8-15-2007;406(1):77-83. View abstract.

Navarro, V., Macarulla, M. T., Fernandez-Quintela, A., Rodriguez, V. M., Simon, E., and Portillo, M. P. Effects of trans-10,cis-12 conjugated linoleic acid on cholesterol metabolism in hypercholesterolaemic hamsters. Eur J Nutr 2007;46(4):213-219. View abstract.

Whigham, L. D., Watras, A. C., and Schoeller, D. A. Efficacy of conjugated linoleic acid for reducing fat mass: a meta-analysis in humans. Am.J Clin.Nutr 2007;85(5):1203-1211. View abstract.

Thrush, A. B., Chabowski, A., Heigenhauser, G. J., McBride, B. W., Or-Rashid, M., and Dyck, D. J. Conjugated linoleic acid increases skeletal muscle ceramide content and decreases insulin sensitivity in overweight, non-diabetic humans. Appl.Physiol Nutr Metab 2007;32(3):372-382. View abstract.

Laso, N., Brugue, E., Vidal, J., Ros, E., Arnaiz, J. A., Carne, X., Vidal, S., Mas, S., Deulofeu, R., and Lafuente, A. Effects of milk supplementation with conjugated linoleic acid (isomers cis-9, trans-11 and trans-10, cis-12) on body composition and metabolic syndrome components. Br.J Nutr 2007;98(4):860-867. View abstract.

Santos-Zago, L. F., Botelho, A. P., and de Oliveira, A. C. Supplementation with commercial mixtures of conjugated linoleic acid in association with vitamin E and the process of lipid autoxidation in rats. Lipids 2007;42(9):845-854. View abstract.

Tsuzuki, T. and Ikeda, I. Slow absorption of conjugated linoleic acid in rat intestines, and similar absorption rates of 9c,11t-conjugated linoleic acid and 10t,12c-conjugated linoleic acid. Biosci.Biotechnol.Biochem. 2007;71(8):2034-2040. View abstract.

Castaneda-Gutierrez, E., Benefield, B. C., de Veth, M. J., Santos, N. R., Gilbert, R. O., Butler, W. R., and Bauman, D. E. Evaluation of the mechanism of action of conjugated linoleic acid isomers on reproduction in dairy cows. J Dairy Sci 2007;90(9):4253-4264. View abstract.

Dauchy, R. T., Dauchy, E. M., Davidson, L. K., Krause, J. A., Lynch, D. T., Tirrell, P. C., Tirrell, R. P., Sauer, L. A., Van der, Riet P., and Blask, D. E. Inhibition of fatty acid transport and proliferative activity in tissue-isolated human squamous cell cancer xenografts perfused in situ with melatonin or eicosapentaenoic or conjugated linoleic acids. Comp Med 2007;57(4):377-382. View abstract.

Yun, H. S., Do, S. H., Jeong, W. I., Yang, H. J., Yuan, D. W., Hong, I. H., Lee, H. R., Lee, I. S., Kim, Y. K., Choi, M. S., Kim, H. A., and Jeong, K. S. Cytotoxic effects of the conjugated linoleic acid isomers t10c12, c9t11-CLA and mixed form on rat hepatic stellate cells and CCl4-induced hepatic fibrosis. J Nutr Biochem. 2008;19(3):175-183. View abstract.

Iwata, T., Kamegai, T., Yamauchi-Sato, Y., Ogawa, A., Kasai, M., Aoyama, T., and Kondo, K. Safety of dietary conjugated linoleic acid (CLA) in a 12-weeks trial in healthy overweight Japanese male volunteers. J Oleo.Sci 2007;56(10):517-525. View abstract.

Wendel, A. A., Purushotham, A., Liu, L. F., and Belury, M. A. Conjugated linoleic acid fails to worsen insulin resistance but induces hepatic steatosis in the presence of leptin in ob/ob mice. J Lipid Res 2008;49(1):98-106. View abstract.

Tarnopolsky, M., Zimmer, A., Paikin, J., Safdar, A., Aboud, A., Pearce, E., Roy, B., and Doherty, T. Creatine monohydrate and conjugated linoleic acid improve strength and body composition following resistance exercise in older adults. PLoS.One. 2007;2(10):e991. View abstract.

Lam, C. K., Chen, J., Cao, Y., Yang, L., Wong, Y. M., Yeung, S. Y., Yao, X., Huang, Y., and Chen, Z. Y. Conjugated and non-conjugated octadecaenoic acids affect differently intestinal acyl coenzyme A: cholesterol acyltransferase activity. Atherosclerosis 2008;198(1):85-93. View abstract.

Stachowska, E., Baskiewicz-Masiuk, M., Dziedziejko, V., Gutowska, I., Baranowska-Bosiacka, I., Marchlewicz, M., Dolegowska, B., Wiszniewska, B., Machalinski, B., and Chlubek, D. Conjugated linoleic acid increases intracellular ROS synthesis and oxygenation of arachidonic acid in macrophages. Nutrition 2008;24(2):187-199. View abstract.

Turpeinen, A. M., Ylonen, N., von Willebrand, E., Basu, S., and Aro, A. Immunological and metabolic effects of cis-9, trans-11-conjugated linoleic acid in subjects with birch pollen allergy. Br.J Nutr 2008;100(1):112-119. View abstract.

Konig, B., Spielmann, J., Haase, K., Brandsch, C., Kluge, H., Stangl, G. I., and Eder, K. Effects of fish oil and conjugated linoleic acids on expression of target genes of PPAR alpha and sterol regulatory element-binding proteins in the liver of laying hens. Br.J Nutr 2008;100(2):355-363. View abstract.

Kim, Y. S., Cerbo, R. M., Hah, C. K., Bahn, K. N., Kim, J. O., and Ha, Y. L. Growth inhibition of osteosarcoma cell MG-63 by a mixture of trans,trans conjugated linoleic acid isomers: possible mechanistic actions. J Food Sci 2008;73(1):T7-15. View abstract.

Ringseis, R., Gahler, S., and Eder, K. Conjugated linoleic acid isomers inhibit platelet-derived growth factor-induced NF-kappaB transactivation and collagen formation in human vascular smooth muscle cells. Eur J Nutr 2008;47(2):59-67. View abstract.

Alibin, C. P., Kopilas, M. A., and Anderson, H. D. Suppression of cardiac myocyte hypertrophy by conjugated linoleic acid: role of peroxisome proliferator-activated receptors alpha and gamma. J Biol.Chem. 4-18-2008;283(16):10707-10715. View abstract.

Raff, M., Tholstrup, T., Basu, S., Nonboe, P., Sorensen, M. T., and Straarup, E. M. A diet rich in conjugated linoleic acid and butter increases lipid peroxidation but does not affect atherosclerotic, inflammatory, or diabetic risk markers in healthy young men. J Nutr 2008;138(3):509-514. View abstract.

Zhou, X. R., Sun, C. H., Liu, J. R., and Zhao, D. Dietary conjugated linoleic acid increases PPAR gamma gene expression in adipose tissue of obese rat, and improves insulin resistance. Growth Horm.IGF.Res 2008;18(5):361-368. View abstract.

Sneddon, A. A., Tsofliou, F., Fyfe, C. L., Matheson, I., Jackson, D. M., Horgan, G., Winzell, M. S., Wahle, K. W., Ahren, B., and Williams, L. M. Effect of a conjugated linoleic acid and omega-3 fatty acid mixture on body composition and adiponectin. Obesity.(Silver.Spring) 2008;16(5):1019-1024. View abstract.

Weiler, H. A., Fitzpatrick, S., and Fitzpatrick-Wong, S. C. Dietary conjugated linoleic acid in the cis-9, trans-11 isoform reduces parathyroid hormone in male, but not female, rats. J Nutr Biochem. 2008;19(11):762-769. View abstract.

Liao, C. H., Shaw, H. M., and Chao, P. M. Impairment of glucose metabolism in mice induced by dietary oxidized frying oil is different from that induced by conjugated linoleic acid. Nutrition 2008;24(7-8):744-752. View abstract.

Ruth, M. R., Taylor, C. G., Zahradka, P., and Field, C. J. Abnormal immune responses in fa/fa Zucker rats and effects of feeding conjugated linoleic acid. Obesity.(Silver.Spring) 2008;16(8):1770-1779. View abstract.

Jaudszus, A., Krokowski, M., Mockel, P., Darcan, Y., Avagyan, A., Matricardi, P., Jahreis, G., and Hamelmann, E. Cis-9,trans-11-conjugated linoleic acid inhibits allergic sensitization and airway inflammation via a PPARgamma-related mechanism in mice. J Nutr 2008;138(7):1336-1342. View abstract.

Islam, M. A., Kim, Y. S., Jang, W. J., Lee, S. M., Kim, H. G., Kim, S. Y., Kim, J. O., and Ha, Y. L. A mixture of trans, trans conjugated linoleic acid induces apoptosis in MCF-7 human breast cancer cells with reciprocal expression of Bax and Bcl-2. J Agric.Food Chem. 7-23-2008;56(14):5970-5976. View abstract.

Tholstrup, T., Raff, M., Straarup, E. M., Lund, P., Basu, S., and Bruun, J. M. An oil mixture with trans-10, cis-12 conjugated linoleic acid increases markers of inflammation and in vivo lipid peroxidation compared with cis-9, trans-11 conjugated linoleic acid in postmenopausal women. J Nutr 2008;138(8):1445-1451. View abstract.

Ramos, R., Mascarenhas, J., Duarte, P., Vicente, C., and Casteleiro, C. Conjugated linoleic acid-induced toxic hepatitis: first case report. Dig.Dis.Sci 2009;54(5):1141-1143. View abstract.

Scatliff, C. E., Bankovic-Calic, N., Ogborn, M. R., and Aukema, H. M. Effects of dietary conjugated linoleic acid in advanced experimental polycystic kidney disease. Nephron Exp.Nephrol. 2008;110(2):e44-e48. View abstract.

Hashem, M. A., Jun, K. Y., Lee, E., Lim, S., Choo, H. Y., and Kwon, Y. A rapid and sensitive screening system for human type I collagen with the aim of discovering potent anti-aging or anti-fibrotic compounds. Mol.Cells 12-31-2008;26(6):625-630. View abstract.

Perez-Cano, F. J., Ramirez-Santana, C., Molero-Luis, M., Castell, M., Rivero, M., Castellote, C., and Franch, A. Mucosal IgA increase in rats by continuous CLA feeding during suckling and early infancy. J Lipid Res 2009;50(3):467-476. View abstract.

Ingelsson, E. and Riserus, U. Effects of trans10cis12CLA-induced insulin resistance on retinol-binding protein 4 concentrations in abdominally obese men. Diabetes Res Clin.Pract. 2008;82(3):e23-e24. View abstract.

Ramirez-Santana, C., Castellote, C., Castell, M., Rivero, M., Rodriguez-Palmero, M., Franch, A., and Perez-Cano, F. J. Long-term feeding of the cis-9,trans-11 isomer of conjugated linoleic acid reinforces the specific immune response in rats. J Nutr 2009;139(1):76-81. View abstract.

Roy, B. D., Bourgeois, J., Rodriguez, C., Payne, E., Young, K., Shaughnessy, S. G., and Tarnopolosky, M. A. Conjugated linoleic acid prevents growth attenuation induced by corticosteroid administration and increases bone mineral content in young rats. Appl.Physiol Nutr Metab 2008;33(6):1096-1104. View abstract.

Drury, B., Warford-Woolgar, L. J., Herchak, D. J., Bankovic-Calic, N., Crow, G., Taylor, C. G., Zahradka, P., Ogborn, M. R., and Aukema, H. M. Dietary trans-10, cis-12 conjugated linoleic acid reduces early glomerular enlargement and elevated renal cyclooxygenase-2 levels in young obese fa/fa zucker rats. J Nutr 2009;139(2):285-290. View abstract.

Amaru, D. L. and Field, C. J. Conjugated linoleic acid decreases mcf-7 human breast cancer cell growth and insulin-like growth factor-1 receptor levels. Lipids 2009;44(5):449-458. View abstract.

Corino, C., Pastorelli, G., Rosi, F., Bontempo, V., and Rossi, R. Effect of dietary conjugated linoleic acid supplementation in sows on performance and immunoglobulin concentration in piglets. J Anim Sci 2009;87(7):2299-2305. View abstract.

Nakamura, Y. K. and Omaye, S. T. Conjugated linoleic acid isomers' roles in the regulation of PPAR-gamma and NF-kappaB DNA binding and subsequent expression of antioxidant enzymes in human umbilical vein endothelial cells. Nutrition 2009;25(7-8):800-811. View abstract.

Zhao, W. S., Zhai, J. J., Wang, Y. H., Xie, P. S., Yin, X. J., Li, L. X., and Cheng, K. L. Conjugated linoleic acid supplementation enhances antihypertensive effect of ramipril in Chinese patients with obesity-related hypertension. Am.J Hypertens. 2009;22(6):680-686. View abstract.

Byeon, J. I., Song, H. S., Oh, T. W., Kim, Y. S., Choi, B. D., Kim, H. C., Kim, J. O., Shim, K. H., and Ha, Y. L. Growth inhibition of foodborne and pathogenic bacteria by conjugated linoleic acid. J Agric.Food Chem. 4-22-2009;57(8):3164-3172. View abstract.

Peterson, K. M., O'Shea, M., Stam, W., Mohede, I. C., Patrie, J. T., and Hayden, F. G. Effects of dietary supplementation with conjugated linoleic acid on experimental human rhinovirus infection and illness. Antivir.Ther 2009;14(1):33-43. View abstract.

Aryaeian, N., Shahram, F., Djalali, M., Eshragian, M. R., Djazayeri, A., Sarrafnejad, A., Naderi, N., Chamari, M., Fatehi, F., and Zarei, M. Effect of conjugated linoleic acid, vitamin E and their combination on lipid profiles and blood pressure of Iranian adults with active rheumatoid arthritis. Vasc.Health Risk Manag. 2008;4(6):1423-1432. View abstract.

Broughton, K. S., Rule, D. C., Ye, Y., Zhang, X., Driscoll, M., and Culver, B. Dietary omega-3 fatty acids differentially influence ova release and ovarian cyclooxygenase-1 and cyclooxygenase-2 expression in rats. Nutr Res 2009;29(3):197-205. View abstract.

Qin, H., Liu, Y., Lu, N., Li, Y., and Sun, C. H. cis-9,trans-11-Conjugated Linoleic Acid Activates AMP-Activated Protein Kinase in Attenuation of Insulin Resistance in C(2)C(12) Myotubes. J Agric.Food Chem. 4-13-2009; View abstract.

Rahman, M., Halade, G. V., El Jamali, A., and Fernandes, G. Conjugated linoleic acid (CLA) prevents age-associated skeletal muscle loss. Biochem.Biophys.Res Commun. 6-12-2009;383(4):513-518. View abstract.

Cornish, S. M., Candow, D. G., Jantz, N. T., Chilibeck, P. D., Little, J. P., Forbes, S., Abeysekara, S., and Zello, G. A. Conjugated linoleic acid combined with creatine monohydrate and whey protein supplementation during strength training. Int J Sport Nutr Exerc.Metab 2009;19(1):79-96. View abstract.

Lee, Y. and Vanden Heuvel, J. P. Inhibition of macrophage adhesion activity by 9trans,11trans-conjugated linoleic acid. J Nutr Biochem. 2010;21(6):490-497. View abstract.

de Veth, M. J., Bauman, D. E., Koch, W., Mann, G. E., Pfeiffer, A. M., and Butler, W. R. Efficacy of conjugated linoleic acid for improving reproduction: a multi-study analysis in early-lactation dairy cows. J Dairy Sci 2009;92(6):2662-2669. View abstract.

Sofi, F., Buccioni, A., Cesari, F., Gori, A. M., Minieri, S., Mannini, L., Casini, A., Gensini, G. F., Abbate, R., and Antongiovanni, M. Effects of a dairy product (pecorino cheese) naturally rich in cis-9, trans-11 conjugated linoleic acid on lipid, inflammatory and haemorheological variables: a dietary intervention study. Nutr Metab Cardiovasc.Dis. 2010;20(2):117-124. View abstract.

Larsson, S. C., Bergkvist, L., and Wolk, A. Conjugated linoleic acid intake and breast cancer risk in a prospective cohort of Swedish women. Am.J Clin.Nutr 2009;90(3):556-560. View abstract.

Raff, M., Tholstrup, T., Toubro, S., Bruun, J. M., Lund, P., Straarup, E. M., Christensen, R., Sandberg, M. B., and Mandrup, S. Conjugated linoleic acids reduce body fat in healthy postmenopausal women. J Nutr 2009;139(7):1347-1352. View abstract.

Norris, L. E., Collene, A. L., Asp, M. L., Hsu, J. C., Liu, L. F., Richardson, J. R., Li, D., Bell, D., Osei, K., Jackson, R. D., and Belury, M. A. Comparison of dietary conjugated linoleic acid with safflower oil on body composition in obese postmenopausal women with type 2 diabetes mellitus. Am.J Clin.Nutr 2009;90(3):468-476. View abstract.

Malovrh, T., Kompan, L., Juntes, P., Wraber, B., Spindler-Vesel, A., and Kompan, D. Influence of conjugated linoleic acid on the porcine immune response and morbidity: a randomized controlled trial. Lipids Health Dis. 2009;8:22. View abstract.

Herrmann, J., Rubin, D., Hasler, R., Helwig, U., Pfeuffer, M., Auinger, A., Laue, C., Winkler, P., Schreiber, S., Bell, D., and Schrezenmeir, J. Isomer-specific effects of CLA on gene expression in human adipose tissue depending on PPARgamma2 P12A polymorphism: a double blind, randomized, controlled cross-over study. Lipids Health Dis. 2009;8:35. View abstract.

Sluijs, I., Plantinga, Y., de Roos, B., Mennen, L. I., and Bots, M. L. Dietary supplementation with cis-9,trans-11 conjugated linoleic acid and aortic stiffness in overweight and obese adults. Am.J Clin.Nutr 2010;91(1):175-183. View abstract.

Schoeller, D. A., Watras, A. C., and Whigham, L. D. A meta-analysis of the effects of conjugated linoleic acid on fat-free mass in humans. Appl.Physiol Nutr Metab 2009;34(5):975-978. View abstract.

Hernandez-Diaz, G., Alexander-Aguilera, A., Arzaba-Villalba, A., Soto-Rodriguez, I., and Garcia, H. S. Effect of conjugated linoleic acid on body fat, tumor necrosis factor alpha and resistin secretion in spontaneously hypertensive rats. Prostaglandins Leukot.Essent.Fatty Acids 2010;82(2-3):105-109. View abstract.

Evans, N. P., Misyak, S. A., Schmelz, E. M., Guri, A. J., Hontecillas, R., and Bassaganya-Riera, J. Conjugated linoleic acid ameliorates inflammation-induced colorectal cancer in mice through activation of PPARgamma. J Nutr 2010;140(3):515-521. View abstract.

Jung, J. I., Cho, H. J., Kim, J., Kwon, D. Y., and Park, J. H. trans-10,cis-12 conjugated linoleic acid inhibits insulin-like growth factor-I receptor signaling in TSU-Pr1 human bladder cancer cells. J Med Food 2010;13(1):13-19. View abstract.

Zhai, J. J., Liu, Z. L., Li, J. M., Chen, J. P., Jiang, L., Wang, D. M., Yuan, J., Shen, J. G., Yang, D. P., and Chen, J. Q. Different mechanisms of cis-9,trans-11- and trans-10,cis-12- conjugated linoleic acid affecting lipid metabolism in 3T3-L1 cells. J Nutr Biochem. 2010;21(11):1099-1105. View abstract.

Wanders, A. J., Brouwer, I. A., Siebelink, E., and Katan, M. B. Effect of a high intake of conjugated linoleic acid on lipoprotein levels in healthy human subjects. PLoS.One. 2010;5(2):e9000. View abstract.

Racine, N. M., Watras, A. C., Carrel, A. L., Allen, D. B., McVean, J. J., Clark, R. R., O'Brien, A. R., O'Shea, M., Scott, C. E., and Schoeller, D. A. Effect of conjugated linoleic acid on body fat accretion in overweight or obese children. Am.J Clin.Nutr 2010;91(5):1157-1164. View abstract.

Brouwer, I. A., Wanders, A. J., and Katan, M. B. Effect of animal and industrial trans fatty acids on HDL and LDL cholesterol levels in humans--a quantitative review. PLoS.One. 2010;5(3):e9434. View abstract.

McClelland, S., Cox, C., O'Connor, R., de Gaetano, M., McCarthy, C., Cryan, L., Fitzgerald, D., and Belton, O. Conjugated linoleic acid suppresses the migratory and inflammatory phenotype of the monocyte/macrophage cell. Atherosclerosis 2010;211(1):96-102. View abstract.

Paek, J., Kang, J. H., Kim, S. S., Son, K. A., Park, M. R., and Yang, M. P. Trans-10, cis-12 conjugated linoleic acid directly enhances the chemotactic activity of porcine peripheral blood polymorphonuclear neutrophillic leukocytes by activating F-actin polymerization in vitro. Res Vet.Sci 2010;89(2):191-195. View abstract.

Aryaeian, N., Shahram, F., Djalali, M., Eshragian, M. R., Djazayeri, A., Sarrafnejad, A., Salimzadeh, A., Naderi, N., and Maryam, C. Effect of conjugated linoleic acids, vitamin E and their combination on the clinical outcome of Iranian adults with active rheumatoid arthritis. Int J Rheum.Dis. 2009;12(1):20-28. View abstract.

Smit, L. A., Baylin, A., and Campos, H. Conjugated linoleic acid in adipose tissue and risk of myocardial infarction. Am.J Clin.Nutr 2010;92(1):34-40. View abstract.

Chao, P. M., Chen, W. H., Liao, C. H., and Shaw, H. M. Conjugated linoleic acid causes a marked increase in liver alpha-tocopherol and liver alpha-tocopherol transfer protein in C57BL/6 J mice. Int J Vitam.Nutr Res 2010;80(1):65-73. View abstract.

Huebner, S. M., Campbell, J. P., Butz, D. E., Fulmer, T. G., Gendron-Fitzpatrick, A., and Cook, M. E. Individual isomers of conjugated linoleic acid reduce inflammation associated with established collagen-induced arthritis in DBA/1 mice. J Nutr 2010;140(8):1454-1461. View abstract.

Hunt, W. T., Kamboj, A., Anderson, H. D., and Anderson, C. M. Protection of cortical neurons from excitotoxicity by conjugated linoleic acid. J Neurochem. 2010;115(1):123-130. View abstract.

MacRedmond, R., Singhera, G., Attridge, S., Bahzad, M., Fava, C., Lai, Y., Hallstrand, T. S., and Dorscheid, D. R. Conjugated linoleic acid improves airway hyper-reactivity in overweight mild asthmatics. Clin.Exp.Allergy 2010;40(7):1071-1078. View abstract.

Halade, G. V., Rahman, M. M., Williams, P. J., and Fernandes, G. Combination of conjugated linoleic acid with fish oil prevents age-associated bone marrow adiposity in C57Bl/6J mice. J Nutr Biochem. 7-23-2010; View abstract.

Venkatramanan, S., Joseph, S. V., Chouinard, P. Y., Jacques, H., Farnworth, E. R., and Jones, P. J. Milk enriched with conjugated linoleic Acid fails to alter blood lipids or body composition in moderately overweight, borderline hyperlipidemic individuals. J Am.Coll.Nutr 2010;29(2):152-159. View abstract.

Ramirez-Santana, C., Castellote, C., Castell, M., Molto-Puigmarti, C., Rivero, M., Perez-Cano, F. J., and Franch, A. Enhancement of antibody synthesis in rats by feeding cis-9,trans-11 conjugated linoleic acid during early life. J Nutr Biochem. 8-4-2010; View abstract.

Stringer, D. M., Zahradka, P., Declercq, V. C., Ryz, N. R., Diakiw, R., Burr, L. L., Xie, X., and Taylor, C. G. Modulation of lipid droplet size and lipid droplet proteins by trans-10,cis-12 conjugated linoleic acid parallels improvements in hepatic steatosis in obese, insulin-resistant rats. Biochim.Biophys.Acta 2010;1801(12):1375-1385. View abstract.

Michishita, T., Kobayashi, S., Katsuya, T., Ogihara, T., and Kawabuchi, K. Evaluation of the antiobesity effects of an amino acid mixture and conjugated linoleic acid on exercising healthy overweight humans: a randomized, double-blind, placebo-controlled trial. J Int Med Res 2010;38(3):844-859. View abstract.

Park, N. Y., Valacchi, G., and Lim, Y. Effect of dietary conjugated linoleic acid supplementation on early inflammatory responses during cutaneous wound healing. Mediators.Inflamm. 2010;2010 View abstract.

Matthews, D. R., Hosker, J. P., Rudenski, A. S., Naylor, B. A., Treacher, D. F., and Turner, R. C. Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985;28(7):412-419. View abstract.

Ip, C., Scimeca, J. A., and Thompson, H. Effect of timing and duration of dietary conjugated linoleic acid on mammary cancer prevention. Nutr Cancer 1995;24(3):241-247. View abstract.

Cunningham, D. C., Harrison, L. Y., and Shultz, T. D. Proliferative responses of normal human mammary and MCF-7 breast cancer cells to linoleic acid, conjugated linoleic acid and eicosanoid synthesis inhibitors in culture. Anticancer Res 1997;17(1A):197-203. View abstract.

Visonneau, S., Cesano, A., Tepper, S. A., Scimeca, J. A., Santoli, D., and Kritchevsky, D. Conjugated linoleic acid suppresses the growth of human breast adenocarcinoma cells in SCID mice. Anticancer Res 1997;17(2A):969-973. View abstract.

Nicolosi, R. J., Rogers, E. J., Kritchevsky, D., Scimeca, J. A., and Huth, P. J. Dietary conjugated linoleic acid reduces plasma lipoproteins and early aortic atherosclerosis in hypercholesterolemic hamsters. Artery 1997;22(5):266-277. View abstract.

Durgam, V. R. and Fernandes, G. The growth inhibitory effect of conjugated linoleic acid on MCF-7 cells is related to estrogen response system. Cancer Lett 6-24-1997;116(2):121-130. View abstract.

Park, Y., Albright, K. J., Liu, W., Storkson, J. M., Cook, M. E., and Pariza, M. W. Effect of conjugated linoleic acid on body composition in mice. Lipids 1997;32(8):853-858. View abstract.

Houseknecht, K. L., Vanden Heuvel, J. P., Moya-Camarena, S. Y., Portocarrero, C. P., Peck, L. W., Nickel, K. P., and Belury, M. A. Dietary conjugated linoleic acid normalizes impaired glucose tolerance in the Zucker diabetic fatty fa/fa rat. Biochem.Biophys.Res Commun. 3-27-1998;244(3):678-682. View abstract.

Sugano, M., Tsujita, A., Yamasaki, M., Noguchi, M., and Yamada, K. Conjugated linoleic acid modulates tissue levels of chemical mediators and immunoglobulins in rats. Lipids 1998;33(5):521-527. View abstract.

Yurawecz, M. P., Roach, J. A., Sehat, N., Mossoba, M. M., Kramer, J. K., Fritsche, J., Steinhart, H., and Ku, Y. A new conjugated linoleic acid isomer, 7 trans, 9 cis-octadecadienoic acid, in cow milk, cheese, beef and human milk and adipose tissue. Lipids 1998;33(8):803-809. View abstract.

Shadman, Z., Rastmanesh, R., Hedayati, M., Taleban, F. A., Saadat, N., Tahbaz, F., and Mehrabi, Y. Effects of conjugated linoleic acid on insulin sensitivity and diabetes markers in type 2 diabetic patients. Iranian Journal of Endocrinology & Metabolism 2009;11(2):221.

Bonet, S. B., Quintanar, R. A., Viana, A. M., Iglesias-Gutierrez, E., and Varela-Moreiras, G. The effects of yogurt with isomer enriched conjugated linoleic acid on insulin resistance in obese adolescents. Revista Espanola de Pediatria 2008;64(1):94-100.

Roman, J. L., Gonzalvez, A. B. M., Luque, A., Iglesias, J. R., Hernandez, M., and Villegas, J. A. Physical activity and milk intake with conjugated linoleic acid (CLA) in healthy people with excess weight. Revista Espanola de Obesidad 2007;5(2):109-118.

Darestani, A. T., Hosseinpanah, F., Tahbaz, F., Amiri, Z., Darestani, R. T., and Hedayati, M. Effects of conjugated linoleic acid supplementation on body composition and leptin concentration in post-menopausal women. Iranian Journal of Endocrinology & Metabolism 2010;12(1):84.

Berven, G., Bye, A., and Hals, O. Safety of conjugated linoleic acid (CLA) in overweight or obese human volunteers. Eur J Lipid Sci Technol 2000;102:455-462.

Atkinson, R. L. Conjugated linoleic acid for altering body composition and treating obesity. Advances in conjugated linoleic acidresearch.Vol 1. 1999;348-353.

Rigano, L., Andolfatto, C., Bonfigli, A., and Rastrelli, F. CLA Glutathione and Sodium DNA for Reducing Hair Loss. Cosmetics & Toiletries 2007;122(10):71-80.

Belury MA, Mahon A, Banni S. The conjugated linoleic acid (CLA) isomer, t10c12-CLA, is inversely associated with changes in body weight and serum leptin in subjects with type 2 diabetes mellitus. J Nutr. 2003;133(1):257S-260S. View abstract.

Chang TY, Li BL, Chang CC, Urano Y. Acyl-coenzyme A:cholesterol acyltransferases. Am J Physiol Endocrinol Metab 2009;297(1): E1-E9. View abstract.

Onakpoya IJ, Posadzki PP, Watson LK, Davies LA, Ernst E. The efficacy of long-term conjugated linoleic acid (CLA) supplementation on body composition in overweight and obese individuals: a systematic review and meta-analysis of randomized clinical trials. Eur J Nutr 2012;51(2):127-34. View abstract.

Carvalho RF, Uehara SK, Rosa G. Microencapsulated conjugated linoleic acid associated with hypocaloric diet reduces body fat in sedentary women with metabolic syndrome. Vasc Health Risk Manag 2012;8:661-7. View abstract.

Jenkins ND, Buckner SL, Baker RB, et, al. Effects of 6 weeks of aerobic exercise combined with conjugated linoleic acid on the physical working capacity at fatigue threshold. J Strength Cond Res 2014;28(8):2127-35. View abstract.

Jenkins ND, Buckner SL, Cochrane KC, et al. CLA supplementation and aerobic exercise lower blood triacylglycerol, but have no effect on peak oxygen uptake or cardiorespiratory fatigue thresholds. Lipids 2014;49(9):871-80. View abstract.

Nortadas R, Barata J. Fulminant hepatitis during self-medication with conjugated linoleic acid. Ann Hepatol. 2012;11(2):265-7. View abstract.

Terasawa N, Okamoto K, Nakada K, Masuda K. Effect of conjugated linoleic acid intake on endurance exercise performance and anti-fatigue in student athletes. J Oleo Sci 2017;66(7):723-33. View abstract.

Madry E, Chudzicka-Strugala I, Grabanska-Martynska K, et al. Twelve weeks CLA supplementation decreases the hip circumference in overweight and obese women. A double-blind randomized, placebo-controlled trial. Acta Sci Pol Technol Aliment 2016;15(1):107-13. View abstract.

Ebrahimi-Mameghani M, Jamali H, Mahdavi R, Kakaei F, Abedi R, Kabir-Mamdooh B. Conjugated linoleic acid improves glycemic response, lipid profile, and oxidative stress in obese patients with non-alcoholic fatty liver disease: a randomized controlled clinical trial. Croat Med J 2016;57(4):331-42. View abstract.

Jaudszus A, Mainz JG, Pittag S, et al. Effects of a dietary intervention with conjugated linoleic acid on immunological and metabolic parameters in children and adolescents with allergic asthma - a placebo-controlled pilot trial. Lipids Health Dis 2016;15:21. View abstract.

Ribeiro AS, Pina FL, Dodero SR, et al. Effect of conjugated linoleic acid associated with aerobic exercise on body fat and lipid profile in obese women: a randomized, double-blinded, and placebo-controlled trial. Int J Sport Nutr Exerc Metab 2016;26(2):135-44. View abstract.

Costa I, Mendonca MD, Cruz E Silva V, Calado S, Viana-Baptista M. Herbal supplements association with reversible cerebral vasoconstriction syndrome: a case report. J Stroke Cerebrovasc Dis 2017;26(3):673-76. View abstract.

Jenkins NDM, Housh TJ, Miramonti AA, et al. Effects of rumenic acid rich conjugated linoleic acid supplementation on cognitive function and handgrip performance in older men and women. Exp Gerontol 2016;85:1-11. View abstract.

Matin S, Nemati A, Ghobadi H, Alipanah-Moghadam R, Rezagholizadeh L. The effect of conjugated linoleic acid on oxidative stress and matrix metalloproteinases 2 and 9 in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2018;13:1449-1454. View abstract.

Murru E, Carta G, Cordeddu L, et al. Dietary conjugated linoleic acid-enriched cheeses influence the levels of circulating n-3 highly unsaturated fatty acids in humans. Int J Mol Sci. 2018;19(6). pii: E1730. View abstract.

Maher T, Deleuse M, Thondre S, Shafat A, Clegg ME. A comparison of the satiating properties of medium-chain triglycerides and conjugated linoleic acid in participants with healthy weight and overweight or obesity. Eur J Nutr 2021;60(1):203-215. View abstract.

Santurino C, López-Plaza B, Fontecha J, et al. Consumption of goat cheese naturally rich in omega-3 and conjugated linoleic acid improves the cardiovascular and inflammatory biomarkers of overweight and obese subjects: A randomized controlled trial. Nutrients. 2020;12(5):1315. View abstract.

Madry E, Malesza IJ, Subramaniapillai M, et al. Body fat changes and liver safety in obese and overweight women supplemented with conjugated linoleic acid: A 12-week randomised, double-blind, placebo-controlled trial. Nutrients. 2020;12(6):1811. View abstract.

Leilami K, Kohansal A, Mohammadi Sartang M, Babajafari S, Sohrabi Z. Adverse effects of conjugated linoleic acids supplementation on circulating lipoprotein (a) levels in overweight and obese individuals: results of a systematic review and meta-analysis of randomized controlled trials. Am J Cardiovasc Dis 2021;11(1):124-135. View abstract.

He Y, Xu K, Li Y, et al. Metabolomic changes upon conjugated linoleic acid supplementation and predictions of body composition responsiveness. J Clin Endocrinol Metab 2022;107(9):2606-2615. View abstract.

Morvaridzadeh M, Estêvão MD, Morvaridi M, et al. The effect of conjugated linoleic acid intake on oxidative stress parameters and antioxidant enzymes: A systematic review and meta-analysis of randomized clinical trials. Prostaglandins Other Lipid Mediat 2022;163:106666. View abstract.

Haghighat N, Shimi G, Shiraseb F, et al. The effects of conjugated linoleic acid supplementation on liver function enzymes and malondialdehyde in adults: A GRADE-assessed systematic review and dose-response meta-analysis. Pharmacol Res 2022;186:106518. View abstract.

Asbaghi O, Shimi G, Naseri K, et al. The effects of conjugated linoleic acid supplementation on blood pressure and endothelial function in adults: A systematic review and dose-response meta-analysis. Eur J Pharmacol 2022;931:175162. View abstract.

Asbaghi O, Ashtary-Larky D, Naseri K, et al. The effects of conjugated linoleic acid supplementation on lipid profile in adults: A systematic review and dose-response meta-analysis. Front Nutr 2022;9:953012. View abstract.

Suksatan W, Putera HD, Abdulkadhim AH, et al. The effect of conjugated linoleic acid supplementation on oxidative stress markers: A systematic review and meta-analysis of randomized controlled trials. Clin Nutr ESPEN 2022;49:121-128. View abstract.

Liang CW, Cheng HY, Lee YH, Liou TH, Liao CD, Huang SW. Effects of conjugated linoleic acid and exercise on body composition and obesity: a systematic review and meta-analysis. Nutr Rev 2023;81(4):397-415. View abstract.

Rastgoo S, Shimi G, Shiraseb F, et al. The effects of conjugated linoleic acid supplementation on inflammatory cytokines and adipokines in adults: A GRADE-assessed systematic review and dose-response meta-analysis. Front Immunol 2023;14:1092077. View abstract.