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Mizushina, Y., Takahashi, N., Hanashima, L., Koshino, H., Esumi, Y., Uzawa, J., Sugawara, F., and Sakaguchi, K. Lucidenic acid O and lactone, new terpene inhibitors of eukaryotic DNA polymerases from a basidiomycete, Ganoderma lucidum. Bioorg.Med.Chem. 1999;7(9):2047-2052. View abstract.

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Zhu, H. S., Yang, X. L., Wang, L. B., Zhao, D. X., and Chen, L. Effects of extracts from sporoderm-broken spores of Ganoderma lucidum on HeLa cells. Cell Biol.Toxicol. 2000;16(3):201-206. View abstract.

Lee, J. M., Kwon, H., Jeong, H., Lee, J. W., Lee, S. Y., Baek, S. J., and Surh, Y. J. Inhibition of lipid peroxidation and oxidative DNA damage by Ganoderma lucidum. Phytother Res 2001;15(3):245-249. View abstract.

Min, B. S., Gao, J. J., Hattori, M., Lee, H. K., and Kim, Y. H. Anticomplement activity of terpenoids from the spores of Ganoderma lucidum. Planta Med. 2001;67(9):811-814. View abstract.

Ma, J., Ye, Q., Hua, Y., Zhang, D., Cooper, R., Chang, M. N., Chang, J. Y., and Sun, H. H. New lanostanoids from the mushroom Ganoderma lucidum. J.Nat.Prod. 2002;65(1):72-75. View abstract.

Gao, J. J., Min, B. S., Ahn, E. M., Nakamura, N., Lee, H. K., and Hattori, M. New triterpene aldehydes, lucialdehydes A-C, from Ganoderma lucidum and their cytotoxicity against murine and human tumor cells. Chem.Pharm.Bull.(Tokyo) 2002;50(6):837-840. View abstract.

Zhong, L., Jiang, D., and Wang, Q. [Effects of Ganoderma lucidum (Leyss ex Fr) Karst compound on the proliferation and differentiation of K562 leukemic cells]. Hunan.Yi.Ke.Da.Xue.Xue.Bao. 1999;24(6):521-524. View abstract.

Futrakul, N., Boongen, M., Tosukhowong, P., Patumraj, S., and Futrakul, P. Treatment with vasodilators and crude extract of Ganoderma lucidum suppresses proteinuria in nephrosis with focal segmental glomerulosclerosis. Nephron 2002;92(3):719-720. View abstract.

Hu, H., Ahn, N. S., Yang, X., Lee, Y. S., and Kang, K. S. Ganoderma lucidum extract induces cell cycle arrest and apoptosis in MCF-7 human breast cancer cell. Int.J.Cancer 11-20-2002;102(3):250-253. View abstract.

Sliva, D., Labarrere, C., Slivova, V., Sedlak, M., Lloyd, F. P., Jr., and Ho, N. W. Ganoderma lucidum suppresses motility of highly invasive breast and prostate cancer cells. Biochem.Biophys.Res.Commun. 11-8-2002;298(4):603-612. View abstract.

Xiao, G. L., Liu, F. Y., and Chen, Z. H. [Clinical observation on treatment of Russula subnigricans poisoning patients by Ganoderma lucidum decoction]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 2003;23(4):278-280. View abstract.

Hsu, M. J., Lee, S. S., Lee, S. T., and Lin, W. W. Signaling mechanisms of enhanced neutrophil phagocytosis and chemotaxis by the polysaccharide purified from Ganoderma lucidum. Br.J.Pharmacol. 2003;139(2):289-298. View abstract.

Sliva, D., Sedlak, M., Slivova, V., Valachovicova, T., Lloyd, F. P., Jr., and Ho, N. W. Biologic activity of spores and dried powder from Ganoderma lucidum for the inhibition of highly invasive human breast and prostate cancer cells. J.Altern.Complement Med. 2003;9(4):491-497. View abstract.

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Lu, Q. Y., Sartippour, M. R., Brooks, M. N., Zhang, Q., Hardy, M., Go, V. L., Li, F. P., and Heber, D. Ganoderma lucidum spore extract inhibits endothelial and breast cancer cells in vitro. Oncol.Rep. 2004;12(3):659-662. View abstract.

Hong, K. J., Dunn, D. M., Shen, C. L., and Pence, B. C. Effects of Ganoderma lucidum on apoptotic and anti-inflammatory function in HT-29 human colonic carcinoma cells. Phytother.Res. 2004;18(9):768-770. View abstract.

Lu, Q. Y., Jin, Y. S., Zhang, Q., Zhang, Z., Heber, D., Go, V. L., Li, F. P., and Rao, J. Y. Ganoderma lucidum extracts inhibit growth and induce actin polymerization in bladder cancer cells in vitro. Cancer Lett. 12-8-2004;216(1):9-20. View abstract.

Hsu, H. Y., Hua, K. F., Lin, C. C., Lin, C. H., Hsu, J., and Wong, C. H. Extract of Reishi polysaccharides induces cytokine expression via TLR4-modulated protein kinase signaling pathways. J.Immunol. 11-15-2004;173(10):5989-5999. View abstract.

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Cheuk, W., Chan, J. K., Nuovo, G., Chan, M. K., and Fok, M. Regression of gastric large B-Cell lymphoma accompanied by a florid lymphoma-like T-cell reaction: immunomodulatory effect of Ganoderma lucidum (Lingzhi)? Int J Surg Pathol 2007;15(2):180-186. View abstract.

Ni, T., Hu, Y., Sun, L., Chen, X., Zhong, J., Ma, H., and Lin, Z. Oral route of mini-proinsulin-expressing Ganoderma lucidum decreases blood glucose level in streptozocin-induced diabetic rats. Int.J.Mol.Med. 2007;20(1):45-51. View abstract.

Wanmuang, H., Leopairut, J., Kositchaiwat, C., Wananukul, W., and Bunyaratvej, S. Fatal fulminant hepatitis associated with Ganoderma lucidum (Lingzhi) mushroom powder. J Med Assoc Thai. 2007;90(1):179-181. View abstract.

Li, E. K., Tam, L. S., Wong, C. K., Li, W. C., Lam, C. W., Wachtel-Galor, S., Benzie, I. F., Bao, Y. X., Leung, P. C., and Tomlinson, B. Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial. Arthritis Rheum 10-15-2007;57(7):1143-1150. View abstract.

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Seto, S. W., Lam, T. Y., Tam, H. L., Au, A. L., Chan, S. W., Wu, J. H., Yu, P. H., Leung, G. P., Ngai, S. M., Yeung, J. H., Leung, P. S., Lee, S. M., and Kwan, Y. W. Novel hypoglycemic effects of Ganoderma lucidum water-extract in obese/diabetic (+db/+db) mice. Phytomedicine. 2009;16(5):426-436. View abstract.

Zhuang, S. R., Chen, S. L., Tsai, J. H., Huang, C. C., Wu, T. C., Liu, W. S., Tseng, H. C., Lee, H. S., Huang, M. C., Shane, G. T., Yang, C. H., Shen, Y. C., Yan, Y. Y., and Wang, C. K. Effect of citronellol and the Chinese medical herb complex on cellular immunity of cancer patients receiving chemotherapy/radiotherapy. Phytother.Res. 2009;23(6):785-790. View abstract.

Liu, J., Shiono, J., Shimizu, K., Kukita, A., Kukita, T., and Kondo, R. Ganoderic acid DM: anti-androgenic osteoclastogenesis inhibitor. Bioorg.Med.Chem.Lett. 4-15-2009;19(8):2154-2157. View abstract.

Oka, S., Tanaka, S., Yoshida, S., Hiyama, T., Ueno, Y., Ito, M., Kitadai, Y., Yoshihara, M., and Chayama, K. A water-soluble extract from culture medium of Ganoderma lucidum mycelia suppresses the development of colorectal adenomas. Hiroshima J.Med.Sci. 2010;59(1):1-6. View abstract.

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van der Hem, L. G., van der Vliet, J. A., Bocken, C. F., Kino, K., Hoitsma, A. J., and Tax, W. J. Prolongation of allograft survival with Ling Zhi-8, a new immunosuppressive drug. Transplant.Proc. 1994;26(2):746. View abstract.

Kawagishi, H., Mitsunaga, S., Yamawaki, M., Ido, M., Shimada, A., Kinoshita, T., Murata, T., Usui, T., Kimura, A., and Chiba, S. A lectin from mycelia of the fungus Ganoderma lucidum. Phytochemistry 1997;44(1):7-10. View abstract.

Park, E. J., Ko, G., Kim, J., and Sohn, D. H. Antifibrotic effects of a polysaccharide extracted from Ganoderma lucidum, glycyrrhizin, and pentoxifylline in rats with cirrhosis induced by biliary obstruction. Biol Pharm Bull. 1997;20(4):417-420. View abstract.

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Zhang X, Jia Y Li Q Niu S Zhu S Shen C. Clinical curative effect investigation of Lingzhi tablet on lung cancer. Chinese Traditional Patent Medicine 2000;22(7):486-488.

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Jin H, Zhang G, Cao X, and et al. Treatment of hypertension by linzhi combined with hypotensor and its effects on arterial, arteriolar and capillary pressure and microcirculation. In: Niimi H, Xiu RJ, Sawada T, and et al. Microcirculatory Approach to Asian Traditional Medicine. New York: Elsevier Science;1996.

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Hijikata Y, Yamada S, Yasuhara A. Herbal mixtures containing the mushroom Ganoderma lucidum improve recovery time in patients with herpes genitalis and labialis. J Altern Complement Med. 2007 Nov;13(9):985-7. View abstract.

Klupp NL, Chang D, Hawke F, Kiat H, Cao H, Grant SJ, Bensoussan A. Ganoderma lucidum mushroom for the treatment of cardiovascular risk factors. Cochrane Database Syst Rev. 2015 Feb 17;2:CD007259. View abstract.

Noguchi M, Kakuma T, Tomiyasu K, Kurita Y, Kukihara H, Konishi F, Kumamoto S, Shimizu K, Kondo R, Matsuoka K. Effect of an extract of Ganoderma lucidum in men with lower urinary tract symptoms: a double-blind, placebo-controlled randomized and dose-ranging study. Asian J Androl. 2008 Jul;10(4):651-8. View abstract.

Noguchi M, Kakuma T, Tomiyasu K, Yamada A, Itoh K, Konishi F, Kumamoto S, Shimizu K, Kondo R, Matsuoka K. Randomized clinical trial of an ethanol extract of Ganoderma lucidum in men with lower urinary tract symptoms. Asian J Androl. 2008 Sep;10(5):777-85. View abstract.

Zhao H, Zhang Q, Zhao L, Huang X, Wang J, Kang X. Spore Powder of Ganoderma lucidum Improves Cancer-Related Fatigue in Breast Cancer Patients Undergoing Endocrine Therapy: A Pilot Clinical Trial. Evid Based Complement Alternat Med. 2012;2012:809614. View abstract.

Hennicke F, Cheikh-Ali Z, Liebisch T, Maciá-Vicente JG, Bode HB, Piepenbring M. Distinguishing commercially grown Ganoderma lucidum from Ganoderma lingzhi from Europe and East Asia on the basis of morphology, molecular phylogeny, and triterpenic acid profiles. Phytochemistry. 2016 Jul;127:29-37. View abstract.

Ríos JL, Andújar I, Recio MC, Giner RM. Lanostanoids from fungi: a group of potential anticancer compounds. J Nat Prod. 2012 Nov 26;75(11):2016-44. View abstract.

Wu DT, Deng Y, Chen LX. Evaluation on quality consistency of Ganoderma lucidum dietary supplements collected in the United States. Sci Rep. 2017 Aug 10;7(1):7792. doi: 10.1038/s41598-017-06336-3. View abstract.

Wang GH, Wang LH, Wang C, Qin LH. Spore powder of Ganoderma lucidum for the treatment of Alzheimer disease: A pilot study.Medicine (Baltimore). 2018 May;97(19):e0636. doi: 10.1097/MD.0000000000010636. View abstract.

Zhong L, Yan P, Lam WC, et al. Coriolus versicolor and Ganoderma lucidum related natural products as an adjunct therapy for cancers: a systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2019;10:703. View abstract.

Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MA, Gusi N, Collado-Mateo D. Ganoderma lucidum effects on mood and health-related quality of life in women with fibromyalgia. Healthcare (Basel) 2020;8(4):520. View abstract.

Pazzi F, Adsuar JC, Domínguez-Muñoz FJ, García-Gordillo MÁ, Gusi N, Collado-Mateo D. Effects of Ganoderma lucidum and Ceratonia siliqua on blood glucose, lipid profile, and body composition in women with fibromyalgia. Nutr Hosp 2021;38(1):139-145. View abstract.

Younger J, Donovan EK, Hodgin KS, Ness TJ. A placebo-controlled, pseudo-randomized, crossover trial of botanical agents for Gulf war illness: Reishi mushroom (Ganoderma lucidum), stinging nettle (Urtica dioica), and Epimedium (Epimedium sagittatum). Int J Environ Res Public Health 2021;18(7):3671. View abstract.

Kogure T, Koiwai A, Fukushi D, et al. Hypereosinophilia with hepatic nodule formation caused by Ganoderma lucidum. Intern Med 2021;60(24):3897-3903. View abstract.